PMID: 6965604Mar 10, 1980Paper

The effect of lesions of the dorsal cap of the inferior olive on the vestibulo-ocular and optokinetic systems of the cat

Brain Research
G M HaddadD A Robinson

Abstract

The gain (eye velocity/head velocity) of the vestibulo-ocular reflex (VOR) of cats was measured in the dark and light for sinusoidal head oscillations at 0.05 and 1.2 Hz with peak velocity of about 30 deg/sec. Animals wore visual reversing prisms chronically and were also subjected to forced oscillation in the light at 0.05 Hz for 2 h per day. Such experience produced adaptive reduction in VOR gain in the dark from 0.85 to 0.10 within about 4 days; qualitatively similar effects were observed at 1.2 Hz. In 4 cats, the dorsal cap of the inferior olive was located electrophysiologically by its responses to visual motion, and bilateral electrolytic lesions were made in or near this structure. The location of lesions was subsequently identified by histology. After lesions, 3 cats were unable to make adaptive changes in VOR gain when confronted with the same reversing prism paradigm; the fourth exhibited appreciable retardation of adaptation. These results imply that the dorsal cap is essential for plastic adaptation of the VOR. However, all cats retained the ability to use reversed vision to reduce VOR gain in the light after lesions. Optokinetic nystagmus (OKN) and optokinetic after nystagmus (OKAN) were measured in a striped optok...Continue Reading

References

Aug 15, 1978·Experimental Brain Research·E L Keller, W Precht

❮ Previous
Next ❯

Citations

Jan 1, 1981·Anatomy and Embryology·F WalbergH Holländer
Jan 1, 1984·Biological cybernetics·P GillisV P Henri
Aug 1, 1986·Italian Journal of Neurological Sciences·D NutiA Federico
Aug 1, 1984·Brain Research Bulletin·K S Türker, T S Miles
Jan 1, 1991·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·M Ito, S Nagao
Sep 1, 1998·Trends in Cognitive Sciences·M Ito
Aug 18, 2009·Nature Neuroscience·Michael C KeJennifer L Raymond
Nov 21, 1998·The European Journal of Neuroscience·J P Welsh, J A Harvey
May 22, 1992·Annals of the New York Academy of Sciences·A E Luebke, D A Robinson
Feb 1, 1982·Journal of Neurology, Neurosurgery, and Psychiatry·R Rudge, B R Chambers
Jun 26, 2004·Annual Review of Neuroscience·Edward S BoydenJennifer L Raymond
Aug 21, 2009·Journal of Neurophysiology·Sergei B YakushinTheodore Raphan
Mar 6, 2002·Acta Oto-laryngologica·Koji KudoKazumi Makishima
Jan 1, 1981·Annals of the New York Academy of Sciences·C M Oman, O L Bock
Sep 7, 2018·Proceedings of the National Academy of Sciences of the United States of America·Yoshiko Kojima, Robijanto Soetedjo
Jul 23, 1998·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·O Pompeiano
Apr 1, 1983·The Journal of Comparative Neurology·R GellmanA R Gibson

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.