The Effect of Limiting the Range of Perimetric Sensitivities on Pointwise Assessment of Visual Field Progression in Glaucoma

Investigative Ophthalmology & Visual Science
S K GardinerShaban Demirel

Abstract

Automated perimetry does not produce reliable estimates of true psychophysical threshold in glaucomatous visual fields when the perimetric threshold falls below 15 to 19 dB. It may be possible to truncate testing at such locations and not use stimuli with very high contrast. However, this can only be recommended if it does not harm the ability to monitor change. This study examined the effect of applying such a cutoff by censoring sensitivities in two existing longitudinal datasets. Series of six visual fields were taken from participants with glaucoma or high-risk ocular hypertension in the Portland Progression Project (P3) and Rotterdam Eye Study (RES). Pointwise linear regression was used to find "progressing" locations, defined as a slope ≤ -1 dB/y with P < 1%. An eye was labeled progressing if ≥3 locations were progressing. This was repeated after setting any sensitivities below the cutoff value C (CdB) to instead equal that value for different integer values of CdB. In the P3 cohort tested using Swedish Interactive Testing Algorithm (SITA) Standard, censoring below 15 to 19 dB did not reduce the number of eyes flagged as progressing. For the RES cohort tested using the Full Threshold algorithm, censoring below 10 dB did n...Continue Reading

Citations

Aug 6, 2016·American Journal of Ophthalmology·Stuart K GardinerShaban Demirel
Oct 25, 2016·Progress in Retinal and Eye Research·C Gustavo De MoraesLeonard A Levin
Feb 18, 2017·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Jack PhuMichael Kalloniatis
Jun 24, 2017·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Jack PhuMichael Kalloniatis
Aug 1, 2018·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Tiffany ArangoWilliam Seiple
Dec 20, 2017·Current Opinion in Ophthalmology·Zhichao Wu, Felipe A Medeiros
Apr 3, 2020·JAMA Ophthalmology·Diana SalazarJoseph Caprioli
Oct 9, 2019·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Mieko YanagisawaRyo Asaoka
Nov 8, 2018·Translational Vision Science & Technology·Andrew TurpinAllison M McKendrick
May 3, 2019·Investigative Ophthalmology & Visual Science·Michael WallIvan Marin-Franch
Sep 4, 2020·Translational Vision Science & Technology·Stuart K Gardiner, Steven L Mansberger
Jan 9, 2019·Translational Vision Science & Technology·Giovanni MontesanoDavid P Crabb
Dec 22, 2020·Translational Vision Science & Technology·Şerife Seda KucurRene Höhn
Dec 29, 2020·Translational Vision Science & Technology·Vasanth MuthusamyAllison M McKendrick
May 8, 2021·Scientific Reports·Takashi OmotoTatsuya Inoue
May 12, 2021·Optometry and Vision Science : Official Publication of the American Academy of Optometry·William H SwansonStephen A Burns
Jun 13, 2021·Eye·Khaldoon O Al-NosairyMichael Bach
Oct 6, 2021·Translational Vision Science & Technology·Giovanni MontesanoDavid P Crabb

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