PMID: 6256617Jan 1, 1980

The effect of lithium chloride on the replication of herpes simplex virus

Medical Microbiology and Immunology
G R SkinnerP Gallimore

Abstract

Lithium chloride inhibited the replication of type 1 and type 2 Herpes simplex virus at concentrations which permitted host cell replication. Virus polypeptide and antigen synthesis were unaffected while viral DNA synthesis was inhibited. The replication of two other DNA viruses, pseudorabies and vaccinia virus, was inhibited but there was no inhibition of two RNA viruses, namely, EMC and influenze virus.

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Related Concepts

Antigens, Viral
Chloride Ion Level
DNA, Viral
Lithium
Polypeptides
Virus Replication
Lithium Chloride
Herpesvirus 16, Cercopithecine

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