The effect of male involvement and a prevention of mother-to-child transmission (PMTCT) intervention on depressive symptoms in perinatal HIV-infected rural South African women

Archives of Women's Mental Health
Karl PeltzerDeborah L Jones

Abstract

This study investigated perinatal depressive symptoms among HIV-infected women enrolled in a cluster-randomized, controlled trial in South Africa. Women (n = 1370) attending 12 community health centers were consecutively enrolled in a two-phase (phase 1 = without a male partner, phase 2 = with a male partner) and two-condition (experimental or control) prevention of mother-to-child transmission (PMTCT) intervention. Women were enrolled at 8-24 weeks pregnant and followed postpartum at 6 weeks and 6 and 12 months (retention rate = 69.8%). Antenatally, 45.4% of women were above the 12-point Edinburgh Postnatal Depression Scale (EPDS) cutoff, 30.2% were above the cutoff at 6 weeks, and 34.2% and 36.9% at 6 months and 12 months postpartum, respectively. In multilevel regression analyses, depressive symptoms decreased over time among women in phase 2 participating in the intervention condition, but neither condition nor phase alone was associated with a decrease in depression. Greater HIV stigma, increased psychological intimate partner violence, less male involvement, lower education, and non-adherence during pregnancy were associated with increased depressive symptoms over the perinatal period. Results indicated that women partici...Continue Reading

References

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Citations

Aug 23, 2020·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Violeta J RodriguezDeborah L Jones
Nov 3, 2020·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Violeta J RodriguezDeborah L Jones
Feb 27, 2021·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Jillian NearyIrene N Njuguna
Nov 19, 2021·Current HIV/AIDS Reports·Jacqueline HoareNicole Phillips

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