PMID: 9185194Jun 1, 1997Paper

The effect of maturation on the ability to stimulate orbital growth using tissue expanders in the anophthalmic cat orbit

Ophthalmic Plastic and Reconstructive Surgery
G W HeinzM A Cepela

Abstract

Tissue expanders were used to stimulate orbital growth at different stages of maturity in the immature anophthalmic cat orbit. Twelve cats had the right globe enucleated at 2 weeks of age and tissue expanders implanted in the orbit. The cats were randomized into four groups (A, B, C, and D). The tissue expanders remained in the nonexpanded state for a preassigned length of time. Orbital volume was determined on each cat using computed tomography (CT) immediately prior to expansion of the implant. Expansion began at age 10 weeks for group A, 15 weeks for group B, and 25 weeks for group C and involved 0.7 cc injections of saline at 2-week intervals until a final volume of 4.5 cc was obtained. Group D remained as a nonexpansion control group. Four to 5 weeks after expansion was completed, a second orbital volume CT was obtained on each animal and compared with the pre-expansion CT. The right orbits of group A, had pre-expansion (week 10) orbital hypoplasia with a volume 26.2% smaller than the left control orbits. Postexpansion (week 25), the right orbital hypoplasia had decreased to a volume 10.3% less than the left control orbits. The right orbits of group B had pre-expansion (week 15) orbital hypoplasia with a volume 35.6% small...Continue Reading

Citations

Oct 16, 1999·Ophthalmology·M D GossmanD M Roberts
Aug 14, 2003·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Gert SantlerRudolf Mossböck
Feb 13, 2001·The British Journal of Ophthalmology·C HintschichL Koornneef
Oct 1, 2011·Orbit·Deepa RaizadaSantosh G Honavar
May 29, 2012·American Journal of Ophthalmology·Guang YangDongmei Li
Oct 21, 2016·The Journal of Craniofacial Surgery·Brad T MorrowThomas D Samson
Mar 19, 2013·Ophthalmic Plastic and Reconstructive Surgery·George K Escaravage, Jonathan J Dutton

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