The Effect of Menopausal Hormone Therapies on Breast Cancer: Avoiding the Risk

Endocrinology and Metabolism Clinics of North America
Valerie A Flores, Hugh S Taylor

Abstract

Estrogen and P treatment results in greater risk of breast cancer than placebo. Treatment with estrogen alone does not increase the risk of breast cancer, may be used by women who have had a hysterectomy, and may even result in a decreased risk of breast cancer. Continued research seeks to improve the understanding of the interplay between estrogen and progestogens that predispose to adverse effects on breast tissue. Caution over this hypothesized benefit is warranted until it is substantiated by data on the incidence of breast cancer in tissue selective estrogen complex users.

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Citations

Jan 23, 2019·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Valerie A FloresNina S Stachenfeld
Mar 2, 2019·Epigenetics : Official Journal of the DNA Methylation Society·Sophia HarlidJack A Taylor
Nov 12, 2021·Bioscience Trends·Siwei ZhangLing Wang
Apr 16, 2021·Endocrine Reviews·Valerie A FloresJoAnn E Manson

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