The effect of metabolic control on fetal nuchal translucency in women with insulin-dependent diabetes: a preliminary study

Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
J L BarthaP W Soothill

Abstract

Diabetes could potentially alter fetal nuchal translucency (NT) measurements mainly by increasing microvascular permeability. The aim of this study was to test this hypothesis. Sixty-five women with pre-pregnancy insulin-dependent diabetes mellitus undergoing NT screening were evaluated. The main outcome measure was the NT measurement, expressed as both absolute measurements and delta values (number of standard deviations by which the observed value differed from the normal mean for the same gestation). The relationships between NT and years of diabetes, insulin dose, glycosylated hemoglobin, and glycemic capillary profiles ('tight' glycemic control) were studied. There was no significant correlation between NT and any of the studied parameters. There were no differences in NT according to the result of either glycosylated hemoglobin or 'tight' control. Metabolic control does not affect the result of ultrasound-determined fetal NT measurement which, when available, seems to be the best option for screening for Down syndrome in women with diabetes mellitus.

References

Jan 4, 1992·BMJ : British Medical Journal·O Brinchmann-HansenK F Hanssen
Dec 1, 1990·Kidney International·E HommelH H Parving
Aug 8, 1987·Lancet·J A Van der MeulenS Grinstein
May 1, 1987·Journal of Neuropathology and Experimental Neurology·E RechthandS I Rapoport
Jan 1, 1995·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·S JacksonS Vyas
Nov 1, 1993·Journal of Reproduction and Fertility·A M SharkeyS K Smith
Dec 1, 1995·British Journal of Obstetrics and Gynaecology·P P PandyaK H Nicolaides
Jun 1, 1996·Prenatal Diagnosis·P GrecoL Selvaggi
Aug 1, 1997·British Journal of Obstetrics and Gynaecology·E M WallaceD A Aitken
Dec 26, 2001·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·F BrausewetterH H Osterhues
Feb 15, 2002·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·T GhiK H Nicolaides
Apr 2, 2002·Human Reproduction·Monique C HaakAdriana C Gittenberger-de Groot

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Citations

Mar 12, 2011·Journal of Perinatal Medicine·Alina Weissmann-BrennerReuven Achiron
May 30, 2009·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Boaz SheizafArnon Wiznitzer
Oct 20, 2005·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·S KelekciS Sonmez
Oct 25, 2013·Prenatal Diagnosis·E TimmermanC M Bilardo
Sep 8, 2012·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Sevsen KulaksizogluSuna Turkoglu
Aug 6, 2004·American Journal of Obstetrics and Gynecology·Kypros H Nicolaides
Jul 28, 2005·Journal of the Society for Gynecologic Investigation·Heinz LeipoldElisabeth Krampl
Aug 28, 2010·Fetal Diagnosis and Therapy·Leona C Y PoonKypros H Nicolaides
Aug 9, 2003·Prenatal Diagnosis

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