The effect of metabolic syndrome defined by various criteria on the development of ischemic stroke subtypes in a general Japanese population

Atherosclerosis
Jun HataYutaka Kiyohara

Abstract

We evaluated the impact of metabolic syndrome (MetS) defined by various criteria on the occurrence of ischemic stroke subtypes in a general Japanese population. A total of 2452 residents of a Japanese community, Hisayama, aged 40 years or older, were followed up for 14 years. To define MetS, we used the original Japanese criteria, the modified Japanese criteria, the International Diabetes Federation (IDF) criteria, the original National Cholesterol Education Program's Adult Treatment Panel III (NCEP) criteria, and the modified NCEP criteria. We substituted a waist circumference of > or = 90 cm in men and > or = 80 cm in women for the values of > or = 85 cm and > or = 90 cm, respectively, in the modified Japanese criteria and for > 102 cm and > 88cm, respectively, in the modified NCEP criteria. Only MetS defined by the modified Japanese criteria showed a significant association with the development of lacunar infarction, and its hazard ratios (HRs) for the development of atherothrombotic and cardioembolic infarction were significant and greater than those of MetS defined by the other criteria: adjusted HRs for lacunar, atherothrombotic and cardioembolic infarction were 1.94 (95% confidence interval (CI), 1.13-3.32; P=0.02), 2.55...Continue Reading

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Citations

Oct 19, 2010·Circulation Journal : Official Journal of the Japanese Circulation Society·Yutaka MiuraHiroaki Shimokawa
Mar 29, 2012·Circulation Journal : Official Journal of the Japanese Circulation Society·Isao Saito
Nov 1, 2013·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Kazufumi NagahamaYusuke Ohya
Sep 21, 2010·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Yasuyuki OhtaKoji Abe
Feb 25, 2014·Atherosclerosis·Angelo ScuteriUNKNOWN MARE Consortium
Aug 30, 2018·The British Journal of Nutrition·Jing ZhaoYing Gao
Jan 1, 2017·JDR Clinical and Translational Research·Y KawashitaT Saito
Jun 19, 2013·Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine·Yutaka Kiyohara

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