The effect of methanol, formaldehyde, and formic acid on growth of Candida boidinii 11 Bh

Biotechnology and Bioengineering
P Pilát, A Prokop

Abstract

The dependence of the specific growth rate of Candida boidinii 11 Bh on methanol concentration follows Monod-type kinetics only in a narrow concentration range (0--0.8 v/v), with a saturation constant of about 19 mmol. With a further increase in methanol concentration of up to 3% v/v, the specific growth rate remains constant. Beyond this level, the growth rate gradually drops to zero, reaching the threshold value at 7.8% v/v. The specific growth rate is also strongly dependent on the size of the inoculum. The biomass yield decreases with an increase in the methanol concentration. Formaldehyde and formic acid, oxidative products of methanol, approximately 100 and ten times, respectively, more toxic to growth than the original substrate.

References

Jan 1, 1974·Folia Microbiologica·O Volfová, P Pilát
Jan 1, 1974·Folia Microbiologica·Z FenclJ Benes
Jul 1, 1970·Biotechnology and Bioengineering·D O Zines, P L Rogers

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Citations

Nov 1, 1976·Biotechnology and Bioengineering·B J ChenG T Tsao
Jun 20, 1983·Mycopathologia·A FahmyC V Stewart
Jan 1, 1976·Folia Microbiologica·P Pilát, A Prokop
Jan 1, 1976·Folia Microbiologica·P PilátA Prokop
May 28, 2004·International Journal of Toxicology·A KavirajN C Saha
Jun 1, 1985·Biotechnology and Bioengineering·I G Minkevich
Nov 1, 1984·Biotechnology and Bioengineering·P Agrawal, H C Lim
Jan 1, 1983·Zeitschrift für allgemeine Mikrobiologie·J D SchneiderG Mirschel
Jan 1, 1983·Zeitschrift für allgemeine Mikrobiologie·J D SchneiderG Mirschel
May 1, 1979·Applied and Environmental Microbiology·C T HouR N Patel
Jul 1, 1978·Applied and Environmental Microbiology·W HirtG T Tsao
Feb 1, 1977·Applied and Environmental Microbiology·B J ChenG T Tsao
Jun 17, 2021·Biotechnology and Bioengineering·Chunjun ZhanYun Chen

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