PMID: 3747500Jul 1, 1986Paper

The effect of microbial contamination on musculocutaneous and random flaps

The Journal of Surgical Research
R C MurphyM Kadowaki

Abstract

Although musculocutaneous flaps have been shown to have the ability to withstand a greater inoculum of bacteria than random flaps, it has not been shown that the musculocutaneous flap has any greater ability to decrease the bacterial population in a contaminated wound. In this series of experiments, granulating wounds were developed containing 10(4), 10(5), or 10(6) bacteria per gram of tissue. These contaminated wounds were then covered either with musculocutaneous flaps, random flaps, or left uncovered as a control. In the heavily contaminated wounds containing 10(6) bacteria per gram of tissue, neither type of flap was able to prevent bacterial proliferation and all flaps dehisced. In the minimally contaminated wounds containing 10(4) bacteria per gram of tissue, both the musculocutaneous and random flaps achieved wound healing and decreased the bacterial level in the wound. However, in the intermediate group containing 10(5) bacteria per gram of tissue, musculocutaneous flaps lowered the bacterial count and allowed wound closure, whereas the random flaps did not control the bacterial growth and failed. Therefore, in the moderately contaminated wound, musculocutaneous flaps are advantageous and can decrease bacterial counts ...Continue Reading

References

Nov 1, 1978·The Journal of Surgical Research·M J Im, J E Hoopes
Oct 1, 1978·American Journal of Surgery·J W FutrellG S Fitz-Hugh
Jul 1, 1978·Annals of Plastic Surgery·F NahaiL O Vasconez
Apr 1, 1974·The Journal of Surgical Research·M C RobsonM G Groskin
Jul 1, 1973·Plastic and Reconstructive Surgery·R K Daniel, H B Williams
Jul 1, 1968·Plastic and Reconstructive Surgery·M B Myers, G Cherry
Jan 1, 1970·Journal of Surgical Oncology·M C Robson, J P Heggers
Jan 1, 1983·British Journal of Plastic Surgery·C Suárez NietoJ C Galán Cortés
Jan 1, 1983·Plastic and Reconstructive Surgery·F J Rybka
Jul 1, 1982·Plastic and Reconstructive Surgery·N Chang, S J Mathes
Jan 1, 1980·Plastic and Reconstructive Surgery·S D Macht, W H Frazier

❮ Previous
Next ❯

Citations

Mar 1, 1996·British Journal of Plastic Surgery·H CostaJ Trigo
Feb 1, 1996·The British Journal of Oral & Maxillofacial Surgery·H SchliephakeF W Neukam
Nov 18, 2000·Plastic and Reconstructive Surgery·B J WilhelmiL G Phillips
Apr 1, 1993·The Australian and New Zealand Journal of Surgery·I O LeitchM C Robson
Dec 1, 1995·European Journal of Orthopaedic Surgery & Traumatology : Orthopédie Traumatologie·V HeppertA Wentzensen
Nov 24, 2011·Acta neurochirurgica·Kartik G KrishnanJoachim K Krauss
Dec 28, 2010·American Journal of Surgery·Yvonne N PierpontWyatt G Payne
May 20, 2014·Journal of Diabetes Research·Angela OatesAndrew J McBain
Nov 29, 2011·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Dustin L Williams, J William Costerton
Jun 5, 2015·International Wound Journal·Yu-Hsin LinJui-Hsiang Lin
Mar 17, 2004·Current Opinion in Infectious Diseases·Ruth Edwards, Keith G Harding
May 7, 1999·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·M C Robson
Apr 1, 2011·Annals of Plastic Surgery·William C LineaweaverFeng Zhang
Jan 1, 1989·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·R R Richards, E H Schemitsch
Dec 4, 2008·Plastic and Reconstructive Surgery·Steffen BaumeisterJeffrey R Marcus
Dec 20, 2007·Plastic and Reconstructive Surgery·Colin Y L WoonLam-Chuan Teoh
Mar 2, 2006·Annals of Plastic Surgery·Ned SnyderLinda G Phillips
Dec 11, 2013·Annals of Plastic Surgery·Nicolas BertheuilEric Watier
Nov 26, 2020·Plastic and Reconstructive Surgery·Elizabeth G ZolperKaren K Evans
May 6, 2021·Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Mikrochirurgie der Peripheren Nerven und Gefässe : Organ der Vereinigung der Deut·Yves HarderGerhard Pierer
Jun 1, 1997·The Surgical Clinics of North America·M C Robson
Apr 9, 2005·Clinics in Plastic Surgery·Kouros Izadi, Parham Ganchi
Feb 1, 1997·The Surgical Clinics of North America·A Del Pino, H Abcarian

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.