The effect of microvascular decompression in patients with multiple sclerosis and trigeminal neuralgia

Neurosurgery
Tiril Sandell, Per Kristian Eide

Abstract

Trigeminal neuralgia (TN) in patients with multiple sclerosis (MS) is thought to be caused by demyelinating plaques within the nerve root entry zone, the trigeminal nucleus, or the trigeminal tracts. To review our experience of microvascular decompression (MVD) in patients with MS and symptomatic TN. All first-time MVDs for symptomatic trigeminal neuralgia in patients with MS performed by the senior author during an 8-year period (1999-2007) in this department were reviewed. The preoperative pain components were differentiated as being 100% episodic pain, > 50% episodic pain, or > 50% constant pain. At follow-up, pain relief was assessed with a standard mail questionnaire; those still having residual pain were further examined in the outpatient clinic or interviewed by phone. Of the 19 MS patients, 15 were available for follow-up. The median observation period was 55 months (range, 17-99 months). At follow-up, 7 of 15 patients (47%) were completely free of their episodic pain, and an additional 4 (27%) had significant relief of episodic pain (ie, worst pain marked as 0 to 3 cm on a 10-cm visual analog scale). Among the subgroup of 8 patients with a constant pain component, all were free of their constant pain, and 4 (50%) were ...Continue Reading

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Citations

Dec 21, 2011·Current Neurology and Neuroscience Reports·Bruce E Pollock
Oct 15, 2013·World Neurosurgery·Ronald Brisman
Dec 2, 2011·Clinical Neurology and Neurosurgery·Lorenzo De Santi, Pasquale Annunziata
Jan 1, 2014·Multiple Sclerosis and Related Disorders·Greg M ThaeraJonathan L Carter
May 21, 2016·Journal of Neurosurgery·Asem SalmaHazem Akil
Jun 22, 2016·Neurosurgery Clinics of North America·Joanna Y WangChetan Bettegowda
Apr 30, 2015·Multiple Sclerosis : Clinical and Laboratory Research·David Q ChenMojgan Hodaie
Mar 13, 2019·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·L BendtsenG Cruccu
Aug 8, 2013·Neurosurgery·Alireza Mohammad-MohammadiGene H Barnett
Jun 18, 2015·Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·V N ShimanskiyD A Odamanov
Feb 21, 2019·The Journal of Headache and Pain·Giulia Di StefanoAndrea Truini
Nov 4, 2015·Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko·V M TyurnikovK V Koval'
Dec 1, 2015·Operative Neurosurgery·Tarik F IbrahimDouglas E Anderson
Dec 1, 2020·Cephalalgia : an International Journal of Headache·Navid NooryStine Maarbjerg
Mar 4, 2020·World Neurosurgery: X·Carolina Venda NovaRicheal Ni Riordain

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