Although mindfulness-based therapy has become a popular treatment, little is known about its efficacy. Therefore, our objective was to conduct an effect size analysis of this popular intervention for anxiety and mood symptoms in clinical samples. We conducted a literature search using PubMed, PsycINFO, the Cochrane Library, and manual searches. Our meta-analysis was based on 39 studies totaling 1,140 participants receiving mindfulness-based therapy for a range of conditions, including cancer, generalized anxiety disorder, depression, and other psychiatric or medical conditions. Effect size estimates suggest that mindfulness-based therapy was moderately effective for improving anxiety (Hedges's g = 0.63) and mood symptoms (Hedges's g = 0.59) from pre- to posttreatment in the overall sample. In patients with anxiety and mood disorders, this intervention was associated with effect sizes (Hedges's g) of 0.97 and 0.95 for improving anxiety and mood symptoms, respectively. These effect sizes were robust, were unrelated to publication year or number of treatment sessions, and were maintained over follow-up. These results suggest that mindfulness-based therapy is a promising intervention for treating anxiety and mood problems in clinic...Continue Reading
Associated Clinical Trials
Effects of Mindfulness Training on the Emotional Experience and (Non-) Acceptance of Emotions in Adolescents
A prospective study of depression and posttraumatic stress symptoms after a natural disaster: the 1989 Loma Prieta Earthquake
An outpatient program in behavioral medicine for chronic pain patients based on the practice of mindfulness meditation: theoretical considerations and preliminary results
Screening for depression in a community sample. Understanding the discrepancies between depression symptom and diagnostic scales
Development and validation of measures of social phobia scrutiny fear and social interaction anxiety
A randomized, wait-list controlled clinical trial: the effect of a mindfulness meditation-based stress reduction program on mood and symptoms of stress in cancer outpatients
The effects of a mindfulness meditation-based stress reduction program on mood and symptoms of stress in cancer outpatients: 6-month follow-up
Mindfulness-based stress reduction and health-related quality of life in a heterogeneous patient population
Pilot evaluation of a mindfulness-based intervention to improve quality of life among individuals who sustained traumatic brain injuries
Mindfulness-based stress reduction in relation to quality of life, mood, symptoms of stress, and immune parameters in breast and prostate cancer outpatients
The efficacy of short-term psychodynamic psychotherapy in specific psychiatric disorders: a meta-analysis
Measuring depressive symptoms among treatment-resistant seizure disorder patients: POMS Depression scale as an alternative to the BDI-II
Impact of mindfulness-based stress reduction (MBSR) on sleep, mood, stress and fatigue symptoms in cancer outpatients
An exploratory mixed methods study of the acceptability and effectiveness of Mindfulness-Based Cognitive Therapy for patients with active depression and anxiety in primary care
Mindfulness-based psychotherapies: a review of conceptual foundations, empirical evidence and practical considerations
Mindfulness meditation alleviates depressive symptoms in women with fibromyalgia: results of a randomized clinical trial
Effectiveness of a meditation-based stress management program as an adjunct to pharmacotherapy in patients with anxiety disorder
One year pre-post intervention follow-up of psychological, immune, endocrine and blood pressure outcomes of mindfulness-based stress reduction (MBSR) in breast and prostate cancer outpatients
The relationship between medical comorbidity and self-rated pain, mood disturbance, and function in older people with chronic pain
Mindfulness training as an intervention for fibromyalgia: evidence of postintervention and 3-year follow-up benefits in well-being
Randomized trial of a meditation-based stress reduction program and cognitive behavior therapy in generalized social anxiety disorder
A non-randomized comparison of mindfulness-based stress reduction and healing arts programs for facilitating post-traumatic growth and spirituality in cancer outpatients
Measuring the psychological impact of mindfulness meditation on health among patients with cancer: a literature review
Effects of a mindfulness-based intervention on psychological distress, well-being, and maternal self-efficacy in breast-feeding mothers: results of a pilot study
Changes in spirituality partly explain health-related quality of life outcomes after Mindfulness-Based Stress Reduction
A randomized controlled trial of mindfulness-based stress reduction to manage affective symptoms and improve quality of life in gay men living with HIV
Effects of mindfulness-based stress reduction on distressed (type D) personality traits: a randomized controlled trial.
A brief mindfulness based intervention for increase in emotional well-being and quality of life in percutaneous coronary intervention (PCI) patients: the MindfulHeart randomized controlled trial
Genetic disorders of intellectual disability: expanding our concepts of phenotypes and of family outcomes
Centering prayer as an alternative to mindfulness-based cognitive therapy for depression relapse prevention
Mindfulness: a systematic review of instruments to measure an emergent patient-reported outcome (PRO)
Randomized clinical trial of adapted mindfulness-based stress reduction versus group cognitive behavioral therapy for heterogeneous anxiety disorders
Mindfulness based intervention in Parkinson's disease leads to structural brain changes on MRI: a randomized controlled longitudinal trial
Exploring compassion: a meta-analysis of the association between self-compassion and psychopathology
The Chinese medicine construct "stagnation" in mind-body connection mediates the effects of mindfulness training on depression and anxiety
Effects of meditation on anxiety, depression, fatigue, and quality of life of women undergoing radiation therapy for breast cancer
The efficacy of mindfulness-based cognitive therapy in recurrent depressed patients with and without a current depressive episode: a randomized controlled trial
Depression and anxiety following psychosis: associations with mindfulness and psychological flexibility
Post-traumatic stress disorder: cognitive hypnotherapy, mindfulness, and acceptance-based treatment approaches
The benefits of dispositional mindfulness in physical health: a longitudinal study of female college students
An evaluative review of outcome research on universal mental health promotion and prevention programs for higher education students
Examining the efficacy of a brief mindfulness-based stress reduction (Brief MBSR) program on psychological health
Emotional benefits of mindfulness-based stress reduction in older adults: the moderating roles of age and depressive symptom severity
Mindfulness-Oriented Recovery Enhancement for Alcohol Dependence: Therapeutic Mechanisms and Intervention Acceptability
Dispositional mindfulness moderates the effects of stress among adolescents: rumination as a mediator
Facing the dreaded: does mindfulness facilitate coping with distressing experiences? A moderator analysis
Mindfulness-based cognitive therapy versus psycho-education for patients with major depression who did not achieve remission following antidepressant treatment: a preliminary analysis
Authors' reply to response to "Mindfulness and psychological well-being: are they related to type of meditation technique practiced?"
Pain attenuation through mindfulness is associated with decreased cognitive control and increased sensory processing in the brain
Randomized controlled trial of mindfulness-based stress reduction delivered to human immunodeficiency virus-positive patients in Iran: effects on CD4⁺ T lymphocyte count and medical and psychological symptoms
Self-referential thinking, suicide, and function of the cortical midline structures and striatum in mood disorders: possible implications for treatment studies of mindfulness-based interventions for bipolar depression
Mindfulness-based cognitive therapy for patients with medically unexplained symptoms: a randomized controlled trial
Mindfulness-based stress reduction for older adults: effects on executive function, frontal alpha asymmetry and immune function
'Third wave' cognitive therapy versus mentalization-based therapy for major depressive disorder. A protocol for a randomised clinical trial
The DARE study of relapse prevention in depression: design for a phase 1/2 translational randomised controlled trial involving mindfulness-based cognitive therapy and supported self monitoring
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