PMID: 7540520Feb 1, 1995Paper

The effect of nasal mucosal vasoconstriction on nasal airflow sensation

Clinical Otolaryngology and Allied Sciences
R W ClarkeA S Jones

Abstract

The correlation between the objective measurement of nasal resistance and nasal airflow sensation is usually regarded as poor. To investigate the relationship between these two parameters 20 healthy volunteers had nasal resistance to airflow measured by rhinomanometry compared with nasal sensation by visual analogue scoring before and after nasal mucosal vasoconstriction using topical 0.1% xylometazoline. The median change in nasal resistance was 0.2 kPal-1s (95% CI 0.08-0.28 kPal-1s) and in nasal sensation 24 mm (95% CI 17 mm-35 mm). A significant relationship between nasal sensation and nasal resistance to airflow was found (Kendall's Rank correlation (P < 0.05). This function can be described by the linear regression equation: dS = 13.2 + 70.dNR where dS = change in nasal sensation and dNR = change in nasal resistance. There may be a much closer relationship between subjective and objective measures of nasal patency than has previously been thought.

References

Oct 1, 1992·Clinical Otolaryngology and Allied Sciences·R W ClarkeI Sherman
Oct 1, 1989·The Journal of Laryngology and Otology·A S JonesL M Durham
Jan 1, 1989·Journal of Applied Physiology·O HilbergO F Pedersen
Jun 1, 1988·Clinical Otolaryngology and Allied Sciences·P F HardcastleR J Prescott
Aug 1, 1987·The Journal of Laryngology and Otology·A S JonesE Beckingham
Jun 1, 1993·Clinical Otolaryngology and Allied Sciences·R W ClarkeA S Jones
Feb 1, 1993·Clinical Otolaryngology and Allied Sciences·J W FairleyS R Ell

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Citations

Jan 15, 2004·American Journal of Respiratory Medicine : Drugs, Devices, and Other Interventions·Johan HellgrenKjell Torén
Feb 28, 2006·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Eli O MeltzerAlan G Harris
Feb 16, 2010·Current Medical Research and Opinion·Ronald EcclesShirley C Chen
Jul 29, 2008·American Journal of Rhinology·Ronald EcclesShirley C Chen
Feb 23, 2020·International Journal of Computer Assisted Radiology and Surgery·Masoud Gh MoghaddamJohn S Rhee

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