The effect of new cross linked hyaluronan gel on quality of life of patients after deep infiltrating endometriosis surgery: a randomized controlled pilot study.

Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology
Murat EkinLevent Yaşar

Abstract

In this prospective randomised placebo-controlled study, we aimed to evaluate the effect of New Cross linked Hyaluronan Gel (NCH gel) on the quality of life of patients who underwent laparoscopic surgery due to Deep Infiltrating Endometriosis (DIE). The intervention group received 40 mL of NCH gel, and the control group had a 40 mL sterile saline solution instilled into the peritoneal cavity following standard laparoscopic procedures. The patients were called in the third and sixth postoperative months and requested to fill the Visual Analogue Scale (VAS), Endometriosis Health Profile (EHP-5), and Short Form for Mental and Physical Health (SF-12) questionnaires. There was a significant reduction in dysmenorrhoea, dyschezia, dyspareunia VAS scores at 3rd, and 6th-month visits in NCH gel group. The postoperative 6th-month EHP-5 scores were significantly lower (1.16 ± 1.51, p-value: .02) in NCH gel group. Besides, NCH gel group had higher SF-12 mental and SF-12 physical scores. Clinical Trials registration number: NCT04023383IMPACT STATEMENTWhat is already known on this subject? Application of solid or liquid physical barriers is believed to be a promising strategy to reduce adhesions after laparoscopic endometriosis surgery. Howe...Continue Reading

References

Dec 1, 1986·American Journal of Obstetrics and Gynecology·R P Jansen, P Russell
Jun 1, 1997·Obstetrics and Gynecology Clinics of North America·B Eskenazi, M L Warner
Dec 10, 1997·Journal of Pediatric and Adolescent Gynecology·M R LauferS J Emans
May 7, 1999·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·W Y Chen, G Abatangelo
Jan 25, 2000·BJOG : an International Journal of Obstetrics and Gynaecology·R GarryJ Hawe
May 8, 2004·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Georgina JonesStephen Kennedy
Dec 14, 2004·Fertility and Sterility·Ahmad HammoudMichael P Diamond
Mar 26, 2011·Seminars in Reproductive Medicine·Sheikha Al-Jabri, Togas Tulandi
Aug 6, 2013·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Paulo Augusto Ayrosa RibeiroJosé Mendes Aldrighi
Dec 25, 2013·Nature Reviews. Endocrinology·Paolo VercelliniLuigi Fedele
Feb 4, 2014·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·V Minas, T Dada
Dec 19, 2014·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Selcuk SelcukCetin Cam
Apr 25, 2015·Journal of Minimally Invasive Gynecology·Chongdong LiuUNKNOWN HyaRegen Adhesion Study Group
Feb 4, 2016·Revista da Associação Médica Brasileira·Alessandra Bernadete Trovó de Marqui
Apr 30, 2016·Journal of Reproductive Immunology·Halima RakhilaMarc Pouliot
Feb 13, 2017·Fertility and Sterility·Sukhbir S Singh, Michael W H Suen
Sep 24, 2018·Journal of Minimally Invasive Gynecology·Fernanda Vieira Lins ArcoverdeRosanne Marie Kho

❮ Previous
Next ❯

Citations

Jan 19, 2021·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Martin HirschUNKNOWN endo:outcomes, an International Collaboration Harmonising Outcomes and Outcome Measures for Endometriosis Research
Jun 3, 2021·International Journal of Environmental Research and Public Health·Evdochia AdoamneiAlberto Manuel Torres-Cantero

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.

Related Papers

Western Journal of Nursing Research
JiSun ChoiNancy Dunton
Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology
Martin Hirschendo:outcomes, an International Collaboration Harmonising Outcomes and Outcome Measures for Endometriosis Research
The American Journal of Dermatopathology
David M ConradSylvia Pasternak
© 2022 Meta ULC. All rights reserved