The effect of nifedipine on exercise-induced asthma

The Journal of Asthma : Official Journal of the Association for the Care of Asthma
S K SharmaJ S Guleria

Abstract

This article describes the effect of nifedipine, a calcium antagonist, on exercise-induced asthma (EIA). Effect of sublingual administration of 20 mg of nifedipine or placebo was studied in randomized double-blind manner on separate days in 19 extrinsic asthmatic subjects. Nifedipine was found to be significantly effective in abolishing the exercise-induced decrease in forced vital capacity (FVC) and maximal expiratory flows (p less than 0.001). There were no significant changes in heart rate and blood pressure after nifedipine.

References

Mar 1, 1979·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·E C DealJ J Jaeger
Sep 1, 1976·The Journal of Allergy and Clinical Immunology·P A Eggleston, J L Guerrant
Jan 1, 1984·Respiration; International Review of Thoracic Diseases·N CrimiA Mistretta
Mar 21, 1981·British Medical Journal·K R Patel

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Citations

Jan 1, 1990·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·S K Sharma, J N Pande
Jan 1, 1987·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·S K SharmaJ S Guleria
Mar 26, 2013·British Journal of Sports Medicine·Vera H M WanrooijKim D G van de Kant
Jan 7, 2016·BMJ Open·Thomas WestergrenSveinung Berntsen

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