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The effect of o-salicylate upon pentose phosphate pathway activity in normal and G6PD-deficient red cells

British Journal of Haematology

Jun 1, 1975

N Worathumrong, A J Grimes

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Abstract

The effect of the major metabolite of aspirin, namely salicylic acid, upon the pentose phosphate pathway (PPP) of normal and G6PD-deficient red cells has been studied. Salicylic acid was shown to inhibit this pathway in proportion to the amount present. At any concentration of this subs...read more

Mentioned in this Paper

Aspirin
G6PD gene
Salicylate Measurement
Salicylate
Urolene Blue
Biochemical Pathway
Metabolic Inhibition
Glucose-6-phosphate Dehydrogenase Measurement
Glucosephosphate Dehydrogenase
Sodium Salicylate
56
1

The effect of o-salicylate upon pentose phosphate pathway activity in normal and G6PD-deficient red cells

British Journal of Haematology

Jun 1, 1975

N Worathumrong, A J Grimes

PMID: 35

DOI: 10.1111/j.1365-2141.1975.tb00536.x

Abstract

The effect of the major metabolite of aspirin, namely salicylic acid, upon the pentose phosphate pathway (PPP) of normal and G6PD-deficient red cells has been studied. Salicylic acid was shown to inhibit this pathway in proportion to the amount present. At any concentration of this subs...read more

Mentioned in this Paper

Aspirin
G6PD gene
Salicylate Measurement
Salicylate
Urolene Blue
56
1

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