The effect of off-hours hospital admission on mortality and clinical outcomes for patients with upper gastrointestinal hemorrhage: A systematic review and meta-analysis of 20 cohorts

United European Gastroenterology Journal
Xian Feng XiaJames Yun Wong Lau

Abstract

The objective of this article is to evaluate the relationship between off-hours hospital admission (weekends, public holidays or nighttime) and mortality for upper gastrointestinal hemorrhage (UGIH). Medline, Embase, Scopus, and the Chinese Biomedical Literature were searched through December 2016 to identify eligible records for inclusion in this meta-analysis. A random-effects model was applied. Twenty cohort studies were included for analysis. Patients with UGIH who were admitted during off-hours had a significantly higher mortality and were less likely to receive endoscopy within 24 hours of admission. In comparison to variceal cases, patients with nonvariceal bleeding showed a higher mortality when admitted during off-hours. However, for studies conducted in hospitals that provided endoscopy outside normal hours, off-hours admission was not associated with an increased risk of mortality. Our study showed a higher mortality for patients with nonvariceal UGIH who were admitted during off-hours, while this effect might be offset in hospitals with a formal out-of-hours endoscopy on-call rotation.

References

Jan 18, 2006·Clinical Medicine : Journal of the Royal College of Physicians of London·L SchmulewitzD Bell
Aug 30, 2008·The New England Journal of Medicine·Ian M GralnekMarc Bardou
Oct 14, 2008·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Abdel Aziz M ShaheenRobert P Myers
Dec 17, 2008·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Ashwin N AnanthakrishnanKia Saeian
Jul 23, 2009·Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie·R P MyersA M Shaheen
Aug 13, 2009·Digestive Diseases and Sciences·Spencer D DornJames M Naessens
May 25, 2011·The American Journal of Gastroenterology·V JairathK R Palmer
Feb 10, 2012·Yonsei Medical Journal·Sun Jeong ByunSang Hoon Ahn
Mar 31, 2012·Chest·Rahul NanchalUNKNOWN from the Milwaukee Initiative in Critical Care Outcomes Research (MICCOR) Group of Investigators
Jul 4, 2012·Alimentary Pharmacology & Therapeutics·N L de GrootUNKNOWN RASTA study group
Jul 25, 2012·World Journal of Gastroenterology : WJG·Young Hoon YounHyojin Park
Mar 29, 2014·Gastrointestinal Endoscopy·Marwan S AbougergiJohn R Saltzman
May 23, 2014·European Journal of Gastroenterology & Hepatology·Maja TufegdzicMiodrag Krstic
Oct 20, 2015·World Journal of Gastroenterology : WJG·Asma AhmedAdrian J Stanley

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