PMID: 9430350Jun 1, 1997Paper

The effect of off-resonance radiofrequency pulse saturation on fMRI contrast

NMR in Biomedicine
A W SongP Jezzard

Abstract

This paper describes the use of off-resonance saturation to further manipulate the blood oxygenation level dependent (BOLD) contrast of fMRI. A customized narrow bandwidth radiofrequency pulse, applied with a range of frequency offsets prior to selection of each slice, was designed and incorporated into a gradient echo EPI sequence. This application takes advantage of the resonance frequency and linewidth differences between the oxygenated and deoxygenated state of blood in human brain during task activation and rest, and is capable of creating an enhancement in the contrast of the BOLD effect. Because of a possible contribution to the signal change from cerebro-spinal fluid, which has a much narrower linewidth and smaller frequency shift compared with the brain tissue, data were also collected using a nulling inversion pulse. The inversion pulse was applied before the off-resonance pulse and data acquisition to eliminate the CSF signal. Functional areas are thus more localized to the brain tissue.

References

Apr 1, 1992·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·R M Weisskoff, S Kiihne
Jun 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·K K KwongR Turner
Jun 1, 1992·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·P A BandettiniJ S Hyde
Jul 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·S OgawaK Ugurbil
Apr 1, 1990·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·S OgawaP Glynn
Oct 1, 1990·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·S Ogawa, T M Lee
Jun 1, 1994·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·R M WeisskoffB R Rosen
Jan 1, 1994·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·R P KennanJ C Gore
Sep 1, 1993·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·R S MenonK Uğurbil
Sep 1, 1993·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·S LaiR Friedland
Feb 1, 1996·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·A W SongJ S Hyde

❮ Previous
Next ❯

Citations

Jan 22, 2000·Molecular Aspects of Medicine·C Boesch
Mar 22, 2018·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Athena E TheyersBradley J MacIntosh
May 2, 2006·Journal of Magnetic Resonance Imaging : JMRI·Stefan Sunaert
Apr 23, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Phillip Zhe SunA Gregory Sorensen
Nov 26, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Tae KimSeong-Gi Kim
Feb 14, 2009·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jun HuaPeter C M van Zijl
Jan 29, 2005·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jinyuan ZhouPeter C M van Zijl
Jun 16, 2009·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Seth A SmithPeter C M van Zijl
Aug 26, 2020·Wellcome Open Research·Tobias C WoodSteven C R Williams
Aug 31, 2019·BioMed Research International·Mario MascalchiStefano Diciotti

❮ Previous
Next ❯

Related Concepts

Related Feeds

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.

Related Papers

Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
R S MenonK Uğurbil
Proceedings of the National Academy of Sciences of the United States of America
B R RosenA M Dale
Electroencephalography and Clinical Neurophysiology
J R IvesD L Schomer
Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
R M MüriC Boesch
© 2021 Meta ULC. All rights reserved