The Effect of Parkinson Disease Tremor Phenotype on Cepstral Peak Prominence and Transglottal Airflow in Vowels and Speech

Journal of Voice : Official Journal of the Voice Foundation
Brittany R Burk, Christopher R Watts

Abstract

The physiological manifestations of Parkinson disease are heterogeneous, as evidenced by disease subtypes. Dysphonia has been well documented as an early and progressively significant impairment associated with the disease. The purpose of this study was to investigate how acoustic and aerodynamic measures of vocal function were affected by Parkinson tremor subtype (phenotype) in an effort to better understand the heterogeneity of voice impairment severity in Parkinson disease. This is a prospective case-control study. Thirty-two speakers with Parkinson disease assigned to tremor and nontremor phenotypes and 10 healthy controls were recruited. Sustained vowels and connected speech were recorded from each speaker. Acoustic measures of cepstral peak prominence (CPP) and aerodynamic measures of transglottal airflow (TAF) were calculated from the recorded acoustic and aerodynamic waveforms. Speakers with a nontremor dominant phenotype exhibited significantly (P < 0.05) lower CPP and higher TAF in vowels compared with the tremor dominant phenotype and control speakers, who were not different from each other. No significant group differences were observed for CPP or TAF in connected speech. When producing vowels, participants with non...Continue Reading

Citations

Oct 1, 2020·American Journal of Speech-language Pathology·Katherine A Brown, Kristie A Spencer
May 16, 2019·The Annals of Otology, Rhinology, and Laryngology·Boquan LiuJack Jiang
Jul 12, 2020·Journal of Neural Transmission·Tereza TykalováMaria Teresa Pellecchia
Jun 22, 2021·Frontiers in Human Neuroscience·Irene Hidalgo-De la GuíaDaniel Palacios-Alonso
Jul 29, 2021·Clinical Parkinsonism & Related Disorders·Matthew Dumican, Christopher Watts
Jul 21, 2021·Journal of Voice : Official Journal of the Voice Foundation·Maria Luiza DinizAna Cristina Côrtes Gama

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