The Effect of Peripheral Neuromodulation on Pain From the Sacroiliac Joint: A Retrospective Cohort Study

Neuromodulation : Journal of the International Neuromodulation Society
Teodor Goroszeniuk

Abstract

To report a retrospective review of the longer-term results of peripheral neuromodulation in 12 patients with significant chronic sacroiliac joint pain who had previously failed multiple conservative and interventional pain therapies. To allow for the assessment of meaningful longer-term outcome, implants for all 12 patients had been in place for a minimum of 18 months to a maximum of 36 months prior to the formal review. Compared to the preimplantation baseline, the longer-term follow-up revealed a significant and sustained reduction in visual analog scale pain scores from 8.7T 1.1 to 1.1T 1.0 (p < 0.001), with a 75% reduction in analgesia requirement, and improvement in pain impact on daily function from 94.1% T 5.9% to 5.8% T 6.0% (p < 0.001). This initial case series has highlighted that SIJ neuromodulation results in the reduction in pain intensity and improved functionality in patients who have already failed conventional medical management and interventional techniques, including RF denervation. These preliminary results merit a prospective randomized trial of peripheral neuromodulation.

References

Jun 1, 1989·RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin·P F DijkstraR Stoeckart
Jan 1, 1995·Spine·A C SchwarzerN Bogduk
Jun 5, 2002·Spine·Joel A VilenskyJeffrey B Kleiner
Feb 7, 2003·Journal of Spinal Disorders & Techniques·Victor KatzJames Reynolds
Aug 12, 2005·The Clinical Journal of Pain·Boris A ZelleSusan George
Mar 18, 2006·Regional Anesthesia and Pain Medicine·Teodor GoroszeniukWolfgang Hamann
Oct 4, 2006·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Ricardo VallejoNinos J Joseph
Nov 23, 2006·American Journal of Physical Medicine & Rehabilitation·Brian S Foley, Ralph M Buschbacher
Nov 30, 2006·The Australian Journal of Physiotherapy·Peter van der Wurff
Dec 1, 2006·Pain Practice : the Official Journal of World Institute of Pain·Phillip S SizerKirk Thompsen
Nov 24, 2007·Regional Anesthesia and Pain Medicine·Steven P CohenRobert W Hurley
Oct 28, 2008·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Paul DreyfussNikolai Bogduk
Jul 10, 2009·Regional Anesthesia and Pain Medicine·Leonardo Kapural
Mar 17, 2010·Pain Practice : the Official Journal of World Institute of Pain·Sabine Sator-KatzenschlagerRudolf Likar
Sep 28, 2010·PM & R : the Journal of Injury, Function, and Rehabilitation·Steve M AydinTodd P Stitik
Mar 31, 2011·Pain Practice : the Official Journal of World Institute of Pain·Teodor GoroszeniukKaren Sanderson
Aug 5, 2011·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Paul VerrillsAdele Barnard
Aug 23, 2011·Neuromodulation : Journal of the International Neuromodulation Society·Abram H BurgherLisa J Stearns
Oct 14, 2011·Neuromodulation : Journal of the International Neuromodulation Society·Robert M Levy
Apr 1, 2010·Neuromodulation : Journal of the International Neuromodulation Society·William Porter McRoberts, Martin Roche
Jul 1, 2007·Neuromodulation : Journal of the International Neuromodulation Society·Richard M PaiciusCheryl Lempert-Cohen
Jan 1, 2008·Neuromodulation : Journal of the International Neuromodulation Society·Panagiotis TheodosiadisSandesha Kothari
Jan 1, 2009·Neuromodulation : Journal of the International Neuromodulation Society·David Abejón, Elliot S Krames
Jan 1, 2009·Neuromodulation : Journal of the International Neuromodulation Society·Paul VerrillsChantelle Sinclair
Oct 1, 2005·Neuromodulation : Journal of the International Neuromodulation Society·Jens Ellrich, Susanne Lamp
Apr 1, 2007·Neuromodulation : Journal of the International Neuromodulation Society·Teodor GoroszeniukWolfgang C Hamann
Dec 4, 2012·Neuromodulation : Journal of the International Neuromodulation Society·Jean-Pierre Van BuytenThomas Smith
Feb 28, 2013·Neuromodulation : Journal of the International Neuromodulation Society·Arun Angelo PatilSoubrata Raikar
Apr 13, 2013·Neuromodulation : Journal of the International Neuromodulation Society·W Porter McRobertsGiancarlo Barolat
Mar 29, 2014·Current Pain and Headache Reports·Teodor Goroszeniuk, David Pang
Oct 12, 2014·Regional Anesthesia and Pain Medicine·Shannon L RobertsEldon Y Loh
Oct 30, 2014·Neuromodulation : Journal of the International Neuromodulation Society·Marin GuentchevJochen Tuettenberg
Sep 20, 2017·Operative Neurosurgery·Marin GuentchevJochen Tuettenberg

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