The effect of peripheral vascular disease on long-term mortality after coronary artery bypass surgery. Northern New England Cardiovascular Disease Study Group

Archives of Surgery
J D BirkmeyerG T O'Connor

Abstract

To examine the effect of peripheral vascular disease (PVD) on long-term mortality after successful myocardial revascularization. We performed a regional cohort study of 2871 consecutive patients discharged alive after coronary artery bypass graft surgery at five tertiary care centers in Maine, New Hampshire, and Vermont between 1987 and 1989. Data reflecting patient characteristics, heart disease severity, and comorbidity were collected prospectively; the presence of clinical and subclinical indicators of PVD was determined by medical record review; and vital status was determined using the National Death Index (mean follow-up, 4.4 years). Five-year mortality following coronary artery bypass graft surgery was substantially higher in the 755 patients with indicators of PVD (20%; 95% confidence interval [CI], 17% to 23%) than in the 2116 patients without PVD (8%, 95% CI, 7 to 9; P<.001). The crude hazard ratio of long-term mortality associated with PVD was 2.77 (95% CI, 2.19 to 3.50; P<.001). After adjusting for their higher comorbidity scores, more advanced cardiac disease, and age, mortality rates in patients with PVD remained twice as high as those in patients without PVD (adjusted hazard ratio, 2.01; 95% CI, 1.57 to 2.58; P<....Continue Reading

Citations

Jan 16, 2007·Internal and Emergency Medicine·Francesca Elisa BovolatoVittorio Pengo
Feb 8, 2000·Cardiovascular Surgery : Official Journal of the International Society for Cardiovascular Surgery·M FusariP Biglioli
Aug 25, 2011·Heart, Lung & Circulation·Edward A CooperMichael P Vallely
Feb 26, 2008·Heart, Lung & Circulation·Michael P VallelyDonald E Ross
Sep 18, 2004·The American Journal of Cardiology·Friederike K KeatingDavid J Schneider
Jul 28, 2004·The Annals of Thoracic Surgery·Daniel J O'RourkeUNKNOWN Northern New England Cardiovascular Disease Study Group
Apr 6, 2004·The Annals of Thoracic Surgery·Shishir KarthikBrian M Fabri
Nov 25, 2005·The Annals of Thoracic Surgery·Cary W AkinsRichard P Cambria
Aug 7, 2003·The Annals of Thoracic Surgery·David C CharlesworthUNKNOWN Northern New England Cardiovascular Disease Study Group
Aug 7, 2003·The Annals of Thoracic Surgery·Donald S LikoskyUNKNOWN Northern New England Cardiovascular Disease Study Group
Apr 1, 2008·Journal of Cardiothoracic and Vascular Anesthesia·Ritesh Maharaj
Aug 21, 2010·Vascular Medicine·Carmen SuárezUNKNOWN REACH Registry Investigators
Aug 16, 2006·Circulation·Beatrice A GolombMichael H Criqui
Mar 28, 2002·Coronary Artery Disease·Rosa SicariUNKNOWN EPIC (Echo Persantine International Cooperative) Study Group
Aug 8, 2002·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·P LoponenM Luther
Apr 1, 2000·Annals of Vascular Surgery·S W ChengJ Wong
Sep 4, 2021·European Journal of Internal Medicine·Emanuele Durante-MangoniRosa Zampino

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