The effect of phytic acid on the resolution of peptides and proteins in capillary electrophoresis

Analytical Biochemistry
G OkafoP Camilleri

Abstract

Studies are reported on the effect of the sodium salt of phytic acid on the resolution of peptides and proteins. Improved separation in the case of peptides is shown to be due to ion-ion pairing interactions between the positively charged peptides and the phytic acid polyanionic species. The improved peak shapes related to the proteins can be interpreted in terms of the sample preconcentration due to injection of analytes from a water medium to one of high ionic strength.

Citations

Feb 11, 2005·Electrophoresis·Julia A FruetelDebbie Padgen
Feb 10, 1998·Electrophoresis·V Dolnik
Dec 10, 1997·Journal of Chromatography. B, Biomedical Sciences and Applications·D Corradini
May 29, 2004·Analytical Chemistry·B PalenzuelaM Valcárcel

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