The effect of pre-hospital intubation on prognosis in infants, children and adolescents with severe traumatic brain injury: A protocol of systematic review and meta-analysis

Medicine
Yichen Guo, Ruilin Li

Abstract

Traumatic brain injury is one of the leading causes of death and sources of heavy societal burden. Hypoxemia and hypercapnia are the 2 common complications of brain injury. Intubation seems to be an effective intervention for preventing the 2 complications in pre-hospital setting. But the results of the existing studies on the effect of pre-hospital intubation on prognosis of patients (aged less than 18) with severe traumatic brain injury are conflict. Thus, in this study, we aim to conduct a systematic review and meta-analysis to evaluate whether pre-hospital intubation is benefit for the prognosis in infants, children and adolescents with severe traumatic brain injury. We will develop a systematic search strategy which includes MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Chinese Biomedical Literature Database, WanFang Data and China National Knowledge Infrastructure. The WHO International Clinical Trials Registry Platform will be searched for the ongoing studies as well. The cohort studies which aim to evaluate the effect of pre-hospital intubation for infants, children and adolescents with severe traumatic brain injury will be selected. The Newcastle-Ottawa Scale will be used for assessing the risk of bi...Continue Reading

References

Feb 15, 2001·Seminars in Pediatric Surgery·A CooperC Welborn
Jul 9, 2003·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·P David AdelsonUNKNOWN World Federation of Pediatric Intensive and Critical Care Societies
Sep 20, 2006·The Journal of Head Trauma Rehabilitation·Jean A LangloisMarlena M Wald
Jul 10, 2007·Progress in Brain Research·Peter Reilly
Sep 6, 2008·Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors·Neeraj BadjatiaUNKNOWN BTF Center for Guidelines Management
Jan 5, 2011·Journal of Clinical Epidemiology·Gordon GuyattHolger J Schünemann
Aug 2, 2011·Journal of Clinical Epidemiology·Gordon H GuyattUNKNOWN GRADE Working Group
Oct 4, 2016·Annals of Emergency Medicine·Daniel W SpaiteDuane Sherrill
Oct 14, 2016·BMJ : British Medical Journal·Jonathan Ac SterneJulian Pt Higgins

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Brain Injury & Trauma

brain injury after impact to the head is due to both immediate mechanical effects and delayed responses of neural tissues.