The effect of preoperative intravenous use of tenoxicam: a prospective, double-blind, placebo-controlled study

Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research
Tamer AkcaSuha Aydin


In this study, we aimed to investigate the postoperative pain relief effect of preoperative tenoxicam usage in patients who undergo elective laparoscopic cholecystectomy or groin hernia repair. Eighty patients undergoing laparoscopic cholecystectomy or groin hernia repair procedures were randomized to receive either physiologic serum at 100 mL (group I, n = 40) or 20 mg iv tenoxicam (group II, n = 40) immediately before induction. Postoperative analgesic requirement, peroperative side effects and complications of drugs, operating time, post-operative mobilization time and pain score, hospitalization time, and patient pleasure were recorded. Postoperative pain was assessed by the visual analogue scale (VAS) on the recovery unit (RU), at 4, 8, and 24 h and every day at the same times in the morning. The RU median VAS score was also not different when Group 1 was compared with Group 2 (p = .97). However, the postoperative 4-h and 8-h median VAS score was significantly less (p = .01 and p = .03, respectively); first postoperative mobilization time was earlier in group 2 (p = .32). The median pain score and intramuscular analgesic requirement of patients were also reduced in Group 2 in postoperative day 1 (p = .015). The median dura...Continue Reading


Jan 1, 1989·Scandinavian Journal of Rheumatology. Supplement·M Schmitt, T W Guentert
Jan 1, 1988·European Journal of Clinical Pharmacology·O G NilsenE Thue
Feb 1, 1994·Clinical Pharmacokinetics·K T OlkkolaM J Mattila
Feb 1, 1997·The Australian & New Zealand Journal of Obstetrics & Gynaecology·R M Scott, P N Jennings
Apr 1, 1997·Surgical Endoscopy·C G Mixter, T R Hackett
Mar 26, 1998·Anaesthesia and Intensive Care·F J MunroG J Wardall
May 14, 1998·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·S T ColbertP W Keane
Jun 23, 1999·Proceedings of the National Academy of Sciences of the United States of America·T D WarnerJ R Vane
Mar 4, 2000·Anaesthesia and Intensive Care·A S RaoK Inbasegaran
Apr 14, 2000·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·L PicoD Fletcher
Mar 22, 2001·Journal of Clinical Anesthesia·A NorrisJ Katz
May 4, 2002·Surgical Endoscopy·U MaestroniA Donini
Jan 25, 2003·Clinical Pharmacology and Therapeutics·Carsten SkarkeJörn Lötsch
Feb 5, 2003·Journal of Pain and Symptom Management·Gertrud AndersenPer Sjøgren
May 8, 2003·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Marian L T BugterBrian Milne

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