The effect of prophylactic hemoclips on the risk of delayed post-endoscopic mucosal resection bleed for upper and lower gastrointestinal lesions: a retrospective cohort study

BMC Gastroenterology
Karen ChangBrian S Lim

Abstract

Endoscopic mucosal resection (EMR) is a minimally invasive procedure used for the treatment of lesions in the gastrointestinal (GI) tract. There is increased usage of hemoclips during EMR for the prevention of delayed bleeding. This study aimed to evaluate the effect of hemoclips in the prevention of delayed bleeding after EMR of upper and lower GI tract lesions. This is a retrospective cohort study using the Kaiser Permanente Southern California (KPSC) EMR registry. Lesions in upper and lower GI tracts that underwent EMR between January 2012 and December 2015 were analyzed. Rates of delayed bleeding were compared between the hemoclip and no-hemoclip groups. Analysis was stratified by upper GI and lower GI lesions. Lower GI group was further stratified by right and left colon. We examined the relationship between clip use and several clinically-relevant variables among the patients who exhibited delayed bleeding. Furthermore, we explored possible procedure-level and endoscopist-level characteristics that may be associated with clip usage. A total of 18 out of 657 lesions (2.7%) resulted in delayed bleeding: 7 (1.1%) in hemoclip group and 11 (1.7%) in no-hemoclip group (p = 0.204). There was no evidence that clip use moderated t...Continue Reading

References

Apr 24, 2003·Gastrointestinal Endoscopy·Kazuhiko ShiojiRintaro Narisawa
Sep 26, 2006·Gastrointestinal Endoscopy·Scott W Rathgaber, Theresa M Wick
Dec 21, 2006·Annals of Internal Medicine·Theodore R LevinJane Schulman
Jul 21, 2009·Diseases of the Colon and Rectum·Alessandro RepiciAlberto Malesci
Oct 24, 2009·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Cynthia W KoDavid Lieberman
Mar 17, 2010·Gastrointestinal Endoscopy·Mandeep SinghNancy Newman
Jun 15, 2010·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Vikneswaran NamasivayamGanapathy A Prasad
Jan 5, 2011·Gastrointestinal Endoscopy·Linda RabeneckLawrence F Paszat
Sep 29, 2011·Gastrointestinal Endoscopy·Deborah A FisherJason A Dominitz
Sep 29, 2011·Gastrointestinal Endoscopy·Lukejohn W DayMa Somsouk
Feb 5, 2013·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Neehar D ParikhAndrew J Gawron
Jul 11, 2013·Diseases of the Colon and Rectum·Gaius Longcroft-WheatonPradeep Bhandari
Feb 1, 2014·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Nicholas G BurgessMichael J Bourke
Oct 27, 2015·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Aarti K RaoTonya Kaltenbach
Apr 2, 2016·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Eduardo AlbénizUNKNOWN Endoscopic Mucosal Resection Endoscopic Spanish Society Group
Jul 3, 2016·Critical Reviews in Oncology/hematology·Antonella De CeglieMassimo Conio
Jul 31, 2019·Gastroenterology·Eduardo AlbénizMónica Enguita-Germán

❮ Previous
Next ❯

Citations

Feb 28, 2021·Journal of Gastroenterology and Hepatology·Tsung-Chieh YangMing-Chih Hou
May 16, 2021·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Ayla S TuranUNKNOWN Prophylactic Clipping Collaborative Group

❮ Previous
Next ❯

Methods Mentioned

BETA
surgical resection

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association
Eduardo AlbénizEndoscopic Mucosal Resection Endoscopic Spanish Society Group
© 2021 Meta ULC. All rights reserved