The effect of prophylactic transpapillary pancreatic stent insertion on clinically significant leak rate following distal pancreatectomy: results of a prospective controlled clinical trial

Annals of Surgery
Farshad FrozanporUrban Arnelo

Abstract

To determine whether prophylactic pancreatic duct stenting reduces pancreatic fistula (PF) formation after distal pancreatectomy (DP). PF causes major morbidity after DP. Transpapillary pancreatic stenting has been proposed to be beneficial in treating established PF and also, prophylactically, to reduce the risk for PF after DP. Patients scheduled for DP during October 2006 to December 2010 were assessed and, if eligible, randomized to DP without (DP) or with stenting before transection of the neck of the gland (DP + stent). DP procedure was standardized and the follow-up period included the first 30 postoperative days. The outcomes were assessed according to the intention to treat analysis principle. : Sixty-four patients were assessed and 58 were randomized to either DP (n = 29) or DP + stent (n = 29). Mean ± SD operation time for DP was 218.8 ± 94.1 compared to 283.3 ± 131.9 for DP + stent (P = 0.052). Clinically significant PF (ISGPF [The International Study Group on Pancreatic Fistula] classification Grade B or C) occurred in 6 DP (22.2%) and 11 (42.3%) DP + stent patients (odds ratio: 2.57, 95% confidence interval 0.78-8.48; P = 0.122). The mean hospital stay for patients without stent was 13.4 ± 6.4 days compared to 19....Continue Reading

References

Jun 22, 2000·International Journal of Pancreatology : Official Journal of the International Association of Pancreatology·C RenouR Laugier
Jun 27, 2002·Gastrointestinal Endoscopy·Jennifer J TelfordDavid L Carr-Locke
Apr 7, 2005·Gastrointestinal Endoscopy·Shyam VaradarajuluPeter B Cotton
Apr 16, 2005·World Journal of Gastroenterology : WJG·Yin-Mo YangYan-Ting Huang
Jul 9, 2005·Surgery·Claudio BassiUNKNOWN International Study Group on Pancreatic Fistula Definition
Mar 12, 2008·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Stefano CrippaClaudio Bassi
Feb 10, 2010·Annals of Surgery·Forough FarrokhyarGordon Guyatt
Mar 10, 2011·World Journal of Surgery·Matthias ReehMaximilian Bockhorn

❮ Previous
Next ❯

Citations

Oct 22, 2013·Langenbeck's Archives of Surgery·Christina HaaneSoeren Torge Mees
Oct 2, 2013·The Lancet Oncology·Werner HartwigMarkus W Büchler
Mar 1, 2016·Current Problems in Surgery·Mariam F EskanderJennifer F Tseng
Jan 2, 2016·The Indian Journal of Surgery·Abhishek MitraShailesh V Shrikhande
Jan 2, 2016·The Indian Journal of Surgery·Ammar A JavedChristopher L Wolfgang
Dec 18, 2014·Surgical Endoscopy·Frédérique MaireAlain Sauvanet
Jun 28, 2014·BioMed Research International·Filip CečkaAlexander Ferko
Oct 16, 2014·World Journal of Surgery·Yoshiaki MurakamiTaijiro Sueda
May 25, 2016·Scandinavian Journal of Gastroenterology·Kjetil Søreide, Knut Jørgen Labori
Jun 22, 2016·Surgery Today·Yoshihiro MiyasakaMasafumi Nakamura
May 23, 2018·The Journal of Trauma and Acute Care Surgery·Nickolas ByrgeRam Nirula
Nov 17, 2016·Annals of Surgical Treatment and Research·Ye Rim ChangSun-Whe Kim
Jun 28, 2013·Journal of Hepato-biliary-pancreatic Sciences·Rintaro YuiA-Hon Kwon
Dec 18, 2013·Journal of Hepato-biliary-pancreatic Sciences·Hiroaki YanagimotoA-Hon Kwon
Mar 26, 2015·World Journal of Gastroenterology : WJG·Yasuhiro Fujino
Nov 10, 2016·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Kai Wang, Ying Fan
Jan 10, 2021·Langenbeck's Archives of Surgery·Dilmurodjon EshmuminovPierre-Alain Clavien
Mar 27, 2019·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Laura MagginoCharles M Vollmer
Mar 25, 2019·La Presse médicale·Florence JeuneSébastien Gaujoux
Jun 29, 2021·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Lev D BubisUNKNOWN HPB CONCEPT team

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.