The effect of puberty on diurnal sodium regulation

American Journal of Physiology. Renal Physiology
B MahlerS Rittig

Abstract

The aim of this study was to investigate the impact of sex and puberty stage on circadian changes in sodium excretion, sodium-regulating hormones, and hemodynamics. Thirty-nine healthy volunteers (9 prepuberty boys, 10 prepuberty girls, 10 puberty boys, and 10 puberty girls) were included. They all underwent a 24-h circadian in-patient study under standardized conditions regarding activity, diet, and fluid intake. Blood samples were drawn every 4 h, and the urine was collected in fractions. Blood pressure and heart rate were noninvasively monitored. Atrial natriuretic peptide (ANP), angiotensin II, aldosterone, and renin were measured in blood. Children in puberty had lower plasma levels of renin (P < 0.05) and angiotensin II (P < 0.05) and a 26% reduction in filtered sodium without changes in sodium excretion compared with prepuberty children. A circadian rhythm in sodium excretion, the renin-angiotensin system, ANP, and blood pressure was found with a midnight ANP peak (P < 0.001), a nighttime decrease in hemodynamic parameters (P < 0.001), an increase in plasma renin (P < 0.001) and angiotensin II (P < 0.001), and a decrease in sodium excretion (P < 0.001) mainly on the basis of increased sodium reabsorption (P < 0.001). The...Continue Reading

References

Aug 1, 1979·Kidney International·K J Van AckerH M Neels
Aug 1, 1976·The Journal of Pediatrics·H P StalkerT A Kotchen
Mar 1, 1975·The Journal of Clinical Endocrinology and Metabolism·J SassardJ F Cier
Mar 15, 1976·Clinica Chimica Acta; International Journal of Clinical Chemistry·A M KappelgaardJ Giese
Apr 1, 1991·Scandinavian Journal of Clinical and Laboratory Investigation·S RittigJ C Djurhuus
Dec 21, 1985·Lancet·G P HodsmanC I Johnston
Feb 1, 1986·Hypertension·J H PrattC A Parkinson
Oct 22, 1987·The New England Journal of Medicine·R D Mosteller
Oct 1, 1995·American Journal of Hypertension·N WiinbergM W Bentzon
Jan 20, 1999·Kidney International·J A MillerD C Cattran
May 23, 2001·Hypertension·J F Reckelhoff
Sep 25, 2001·Journal of Applied Physiology·N S StachenfeldD L Keefe
Jan 28, 2004·Hypertension·Charlotte HadtsteinUNKNOWN German Study Group for Pediatric Hypertension
May 26, 2004·Cardiovascular Research·Michele Melo Silva-AntonialliDorothy Nigro
Jun 29, 2006·American Journal of Physiology. Renal Physiology·K KamperisJ C Djurhuus
Aug 18, 2006·Journal of the American Society of Nephrology : JASN·Judith A MillerJames W Scholey
Aug 31, 2006·Hypertension·Amit Sachdeva, Alan B Weder
Dec 5, 2006·Current Opinion in Nephrology and Hypertension·Antoinette Pechere-Bertschi, Michel Burnier
Jun 4, 2010·American Journal of Physiology. Renal Physiology·Konstantinos KamperisJens Christian Djurhuus
Sep 29, 2011·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Ana Cristina Simões E Silva, Joseph T Flynn
Oct 21, 2011·American Journal of Physiology. Renal Physiology·B MahlerS Rittig

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Citations

Nov 28, 2017·Chronobiology International·Stefanos NikolaidisVassilis Mougios
Jan 1, 2016·American Journal of Physiology. Renal Physiology·Michelle L Gumz
Apr 22, 2017·Frontiers in Physiology·Tonja W EmansC T Paul Krediet

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