The effect of resistant dextrin as a prebiotic on metabolic parameters and androgen level in women with polycystic ovarian syndrome: a randomized, triple-blind, controlled, clinical trial

European Journal of Nutrition
Sevda Gholizadeh ShamasbiMojgan Mirghafourvand

Abstract

Polycystic ovary syndrome (PCOS) is one of the most common abnormalities in women of reproductive age that can lead to a variety of metabolic and reproductive disorders. Studies reveal that a healthy diet is the most effective way for treating the risk factors associated with metabolic disorders and place greater emphasis on the consumption of prebiotic foods. The present study aims to determine the effect of resistant Dextrin on metabolic parameters, including lipid profile, fasting blood glucose (FBS) and high sensitivity C-reactive protein (hsCRP), and androgen levels, including serum levels of dehydroepiandrosterone sulfate (DHEA-S) and free testosterone, as the primary outcomes, and manifestations of PCOS including menstrual cycle irregularity and hirsutism, as the secondary outcomes. This randomized, controlled, triple-blind, clinical trial was conducted on 62 women aged 18-45 in Tabriz, Iran, in 2016-2017. The participants were divided into a prebiotic group and a placebo group using block randomization. The prebiotic group consumed 20 g of resistant dextrin dissolved in a glass of water and the placebo group 20 g of maltodextrin also dissolved in a glass of water on a daily basis for 3 months. To measure the serum lipid...Continue Reading

References

Aug 1, 1997·The British Journal of Nutrition·A PedersenJ M Van Amelsvoort
Jul 8, 1999·The Journal of Nutrition·N M Delzenne, N N Kok
Feb 16, 2000·The British Journal of Nutrition·H P KruseM Blaut
Apr 18, 2002·Critical Reviews in Biotechnology·Rudrapatnam N Tharanathan
May 13, 2003·The Proceedings of the Nutrition Society·Christine Cherbut
Jun 17, 2003·Clinical Obstetrics and Gynecology·Jean-Patrice BaillargeonJohn E Nestler
Aug 5, 2003·Journal of Lipid Research·Dominique LetexierMichel Beylot
Jun 29, 2004·European Journal of Clinical Nutrition·E G H M van den HeuvelA F M Kardinaal
Sep 24, 2004·Best Practice & Research. Clinical Obstetrics & Gynaecology·Adam Balen
Nov 4, 2004·Hormone Research·Mahin HashemipourSassan Haghighi
Feb 8, 2005·European Journal of Nutrition·Ellen G H M van den HeuvelAlwine F M Kardinaal
Mar 22, 2006·The Journal of Nutrition·Cheryl L DikemanGeorge C Fahey
Oct 24, 2007·The Journal of Nutrition·Sofia Kolida, Glenn R Gibson
Feb 7, 2008·The Journal of Clinical Endocrinology and Metabolism·Mihaela CosmaVictor M Montori
Oct 17, 2008·Diabetes Research and Clinical Practice·L ZhangUNKNOWN DECODE Study Group
May 16, 2009·Current Pharmaceutical Design·Patrice D Cani, Nathalie M Delzenne
Feb 18, 2011·The Cochrane Database of Systematic Reviews·Lisa J MoranHelena J Teede
Jun 2, 2011·Human Reproduction Update·Konstantinos A ToulisBasil C Tarlatzis
Sep 9, 2011·Digestive Diseases and Sciences·Michele MalaguarneraFabio Galvano

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Citations

Sep 13, 2019·Journal of the American College of Nutrition·Gamze Yurtdaş, Yasemin Akdevelioğlu
Jan 8, 2021·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Rachel G ArmaniMaria Eugênia F Canziani
Jan 1, 2021·Journal of the Endocrine Society·Maryan G Rizk, Varykina G Thackray
Mar 7, 2021·International Journal of Molecular Sciences·Pierluigi GiampaolinoLuigi Della Corte
May 28, 2021·Current Obesity Reports·Jaime M MooreMelanie Cree-Green
Jul 6, 2021·Veterinary World·Luiz Eduardo RodriguesHermann Bremer-Neto
Jul 22, 2021·Critical Reviews in Food Science and Nutrition·Yuling LiJiaqi Shuai

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