The effect of ruthenium red and Concanavalin A on the vitelline surface of fertilized and unfertilized rabbit ova

The Anatomical Record
M GordonP V Dandekar


Fertilized and unfertilized rabbit ova exposed to ruthenium red with the zona intact or after mechanical removal, for the demonstration of mucopolysaccharides on the surface coat. Ova were also exposed to Concanavalin A. Ruthenium red bound strongly to elements of the zona and increased the opacity of the plasmalemma. There was no notable change in staining of the vitellus following fertilization. Although there were ruthenium red stained bodies resembling cortical granules in crypts in the plasmalemma, there was no evidence for cortical granule extrusion of mucopolysaccharides. The Concanavalin reaction was seen over both unfertilized and fertilized ova, demonstrating receptors for terminal alpha-D-mannopyranosyl, alpha-D-glycopyranosyl, beta-D-fructofuranyosyl residues. The deposit on the fertilized egg surface was enormously enhanced indicating a change in the distribution of receptor sites.


Feb 1, 1968·Virology·A Martinez-Palomo, C Brailovski
Aug 1, 1969·Proceedings of the National Academy of Sciences of the United States of America·M Inbar, L Sachs
Jun 1, 1972·Biology of Reproduction·C B Metz
Feb 1, 1974·Experimental Cell Research·T OikawaR YANAGIMACHI
Feb 1, 1974·Experimental Cell Research·D O'DellA Monroy
Jan 26, 1973·Nature·T OikawaG L Nicolson
Jan 1, 1974·Journal of Reproduction and Fertility·M GordonW Bartoszewicz
Mar 1, 1966·Experimental Cell Research·R Hadek
Sep 1, 1969·Biology of Reproduction·R StambaughL Mastroianni
Jan 1, 1971·Experimental Cell Research·W Bernhard, S Avrameas
Jun 1, 1971·Journal of Reproduction and Fertility·G W Cooper, J M Bedford
Aug 1, 1954·Australian Journal of Biological Sciences·A W BRADENH A DAVID
Apr 1, 1956·Experimental Cell Research·C R AUSTIN
Dec 1, 1961·The Journal of Experimental Zoology·R YANAGIMACHI, M C CHANG
Oct 1, 1964·Journal of Reproduction and Fertility·P SOUPART, R W NOYES


Jan 4, 2001·Molecular Reproduction and Development·T Hoodbhoy, P Talbot
Dec 1, 1994·Molecular Reproduction and Development·T Hoodbhoy, P Talbot
Mar 1, 1977·The Histochemical Journal·S B Coghill, D Hopwood
Jul 1, 1976·Experimental Cell Research·J RowinskiH Koprowski
Nov 18, 2011·Reproductive Biology and Endocrinology : RB&E·Min Liu
Jan 1, 1986·Progress in Histochemistry and Cytochemistry·E J Sanders
Mar 1, 1981·Experimental Cell Research·M De Felici, G Siracusa
Feb 1, 1980·The Anatomical Record·L V Johnson, P G Calarco
Apr 1, 1988·The Journal of Experimental Zoology·G N CherrD F Katz
Aug 10, 1982·The Journal of Experimental Zoology·Z BinorD P Wolf
Jun 1, 1977·The Journal of Experimental Zoology·M KonwinskiH Koprowski

Related Concepts

Concanavalin A
Polyspermic Fertilization
Levulosa Ife
Glucose, (beta-D)-Isomer
Peptide Hydrolases
Receptors, Drug

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Synthetic Genetic Array Analysis

Synthetic genetic arrays allow the systematic examination of genetic interactions. Here is the latest research focusing on synthetic genetic arrays and their analyses.

Congenital Hyperinsulinism

Congenital hyperinsulinism is caused by genetic mutations resulting in excess insulin secretion from beta cells of the pancreas. Here is the latest research.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Epigenetic Memory

Epigenetic memory refers to the heritable genetic changes that are not explained by the DNA sequence. Find the latest research on epigenetic memory here.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Femoral Neoplasms

Femoral Neoplasms are bone tumors that arise in the femur. Discover the latest research on femoral neoplasms here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.