The effect of sarcopenia on perioperative complications in abdominally based free-flap breast reconstruction.

Journal of Surgical Oncology
Justin M BroylesMark V Schaverien

Abstract

The identification of patient-specific risk factors, which predict morbidity following abdominally based microvascular breast reconstruction is difficult. Sarcopenia is a proxy for patient frailty and is an independent predictor of complications in a myriad of surgical disciplines. We predict that sarcopenic patients will be at higher risk for surgical complications following abdominally based microvascular breast reconstruction. A retrospective study of all patients who underwent delayed abdominally based autologous breast reconstruction following postmastectomy radiation therapy from 2007 to 2013 at a single institution was conducted. Univariate and multiple logistic regression models were used to assess the effect of sarcopenia on postoperative outcomes. Two hundred and eight patients met the inclusion criteria, of which 30 met criteria for sarcopenia (14.1%). There were no significant differences in demographics between groups. There were no significant differences in minor (36.7% vs 44.4%; P = .43) or major (16.7% vs 25.3%; P = .36) complications between groups as well as hospital length of stay. Multivariable logistic regression demonstrated that a staged reconstruction with the use of a tissue expander was the only consi...Continue Reading

References

Jul 1, 1997·Age and Ageing·A J Campbell, D M Buchner
May 6, 2008·Plastic and Reconstructive Surgery·Raj M VyasChristopher A Crisera
Oct 17, 2008·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Marina MourtzakisVickie E Baracos
Nov 22, 2008·Journal of General Internal Medicine·Judy Y ChenKatherine L Kahn
Aug 12, 2009·Current Opinion in Supportive and Palliative Care·Carla M M PradoVickie E Baracos
Jun 1, 2010·Journal of the American College of Surgeons·Martin A MakaryLinda P Fried
Aug 4, 2010·Plastic and Reconstructive Surgery·Christopher J Pannucci, Edwin G Wilkins
Jan 11, 2011·Journal of Vascular Surgery·Jay Soong-Jin LeeUNKNOWN Michigan Analytic Morphomics Group (MAMG)
May 28, 2011·Plastic and Reconstructive Surgery·Shareef JandaliJoseph M Serletti
Jun 14, 2012·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Peter PengTimothy M Pawlik
Jul 14, 2012·Annals of Surgery·Michael J EnglesbeStewart C Wang
Jan 29, 2013·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·K H SheetzA C Chang
May 1, 2013·Plastic and Reconstructive Surgery·John P FischerSuhail Kanchwala
Jul 6, 2013·Calcified Tissue International·René RizzoliOlivier Bruyère
Jan 8, 2015·Annals of Surgical Oncology·Yuji MiyamotoHideo Baba
Jan 9, 2015·Clinical Cases in Mineral and Bone Metabolism : the Official Journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases·Valter SantilliMarco Paoloni
Sep 9, 2015·Journal of Surgical Oncology·Bassim El-SabawiKetan M Patel
Sep 12, 2015·Clinical Transplantation·Patrick W UnderwoodSeth A Waits
Dec 24, 2015·Sarcoma·Robert J WilsonGinger E Holt
Dec 19, 2016·The Breast : Official Journal of the European Society of Mastology·Nicole IlonzoAye Moe Thu Ma
Jun 13, 2017·Inflammatory Bowel Diseases·Mark PedersenPeter Nau
Jul 16, 2017·The Spine Journal : Official Journal of the North American Spine Society·Raphaële Charest-MorinAlana M Flexman
Jan 20, 2018·Nutrition and Cancer·Bianca Umbelino de SouzaCarla Maria Avesani
Feb 13, 2018·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·D WagnerP Kornprat
Sep 4, 2018·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Leandra A BarnesArash Momeni
Nov 14, 2018·The Aging Male : the Official Journal of the International Society for the Study of the Aging Male·Gulistan BahatMehmet Akif Karan

❮ Previous
Next ❯

Citations

Aug 26, 2021·Journal of Plastic Surgery and Hand Surgery·Barkat AliRohini G McKee

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.