Abstract
Chemotherapy-induced alopecia (CIA) remains a distressing adverse event of cancer treatment but may be prevented by scalp cooling. The effectiveness of scalp cooling, however, is dependent on the chemotherapy regimen with successful hair preservation (i.e., < 50% hair loss) in 41-59% of women on taxane-based therapies in comparison to 16-36% on anthracycline-based therapies. Despite the potential utility, use of scalp cooling has shown a more equivocal impact on quality of life (QoL). In this review, we aim to evaluate the use of scalp cooling for CIA and quantitative QoL measures. A systematic review of PubMed, Embase, Web of Science, and Cochrane databases for clinical studies on scalp cooling to prevent CIA published before October 29, 2018 was performed. Clinical studies with 5 or more patients that reported on a quantitative QoL measure were included and graded according to a modified five-point scale from the Oxford Centre for Evidence-Based Medicine. Studies meeting inclusion criteria included 4 randomized clinical trials (RCT), 8 cohort studies, and 1 cross-sectional study with 1282 unique patients. The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (QLQ-C30: 46%) and Br...Continue Reading
References
Oct 1, 1996·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·M A SprangersN K Aaronson
Sep 27, 2002·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Christel ProtièreDominique Genre
Jun 6, 2003·European Journal of Cancer Care·C MacduffH Archibald
Mar 25, 2006·Cancer Nursing·Maria BrowallElla Danielson
Aug 28, 2007·Psycho-oncology·Julie LemieuxLouise Provencher
Jul 22, 2009·PLoS Medicine·David MoherUNKNOWN PRISMA Group
Jul 29, 2009·Psycho-oncology·Corina J G van den HurkWim P M Breed
Nov 1, 2009·Journal of Evidence-based Medicine·Mike Clarke, Li Youping
Jan 1, 2014·Annals of Oncology : Official Journal of the European Society for Medical Oncology·J ChoS J Nam
Mar 26, 2014·Psycho-oncology·Eun Kyung ChoiJuhee Cho
Feb 15, 2017·JAMA : the Journal of the American Medical Association·Dawn L Hershman
Feb 15, 2017·JAMA : the Journal of the American Medical Association·Julie NangiaMothaffar Rimawi
Feb 15, 2017·JAMA : the Journal of the American Medical Association·Hope S RugoTessa Cigler
Sep 25, 2017·Clinical Breast Cancer·Hope S Rugo, Jeffrey Voigt
Jul 27, 2018·The Breast : Official Journal of the European Society of Mastology·Arlene ChanChristopher Reid
Sep 27, 2018·Breast Cancer Research and Treatment·Katharina SmetanayFrederik Marmé
Oct 1, 2017·Annals of Oncology : Official Journal of the European Society for Medical Oncology·F CarlaE L Simoncini
Oct 1, 2017·Annals of Oncology : Official Journal of the European Society for Medical Oncology·T ProchiloA Zaniboni
Citations
Sep 23, 2020·International Journal of Nursing Practice·Rebecca PedersiniAlfredo Berruti
Aug 27, 2019·Frontiers in Oncology·Takayuki KinoshitaMasakazu Toi
Oct 30, 2020·European Journal of Oncology Nursing : the Official Journal of European Oncology Nursing Society·Vanessa BolandAmanda Drury
Feb 18, 2020·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Marit L Bovbjerg, Veronica Irvin
Jan 30, 2021·The Oncologist·Asma DilawariChiranjeev Dash
Aug 18, 2021·Gynecologic Oncology Reports·Cristina MitricSusie Lau
Sep 17, 2021·JCO Oncology Practice·Madison NoviceMonika L Burness