The effect of scalp ischaemia on measurement of cerebral blood volume by near-infrared spectroscopy

Physiological Measurement
H Owen-ReeceD T Delpy

Abstract

Near-infrared spectroscopy (NIRS) is a noninvasive method of quantifying changes in cerebral haemodynamics from changes in the absorption of near-infrared light by oxyhaemoglobin and deoxyhaemoglobin. Measurement of neonatal cerebral blood volume (CBV) by NIRS was described in 1990 but it has been suggested that, in adults, scalp and skull blood content contribute a significant amount to the cerebral haemodynamic variables quantifiable by NIRS. To investigate this, CBV was measured in nine adult subjects, in the frontal region of the head, before and after inflating a pneumatic tourniquet proximal to the measurement site. Because a change in scalp blood content could potentially alter the pathlength of light passing through the head and hence affect the measured CBV, the optical pathlength factor was therefore also measured before and after tourniquet inflation. Blood flow occlusion was confirmed by laser Doppler velocimetry. The results showed that tourniquet inflation had no effect on the estimated value of CBV or the differential pathlength factor. We conclude that, provided the distance between light entry and exit on the surface of the scalp is sufficiently large, changes in scalp blood flow have no effect on NIRS measurem...Continue Reading

References

Sep 1, 1990·Journal of Applied Physiology·N B HampsonC A Piantadosi
Feb 1, 1990·Brain : a Journal of Neurology·K L LeendersS Herold
Mar 1, 1990·Journal of Applied Physiology·J S WyattE O Reynolds
Dec 1, 1988·Physics in Medicine and Biology·D T DelpyJ Wyatt
Jun 1, 1986·Scandinavian Journal of Clinical and Laboratory Investigation·L FribergJ Bülow
Dec 1, 1994·Journal of Applied Physiology·C E ElwellE O Reynolds

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Citations

Mar 13, 2012·European Journal of Applied Physiology·Stylianos N KounalakisIgor B Mekjavic
Jan 9, 2003·Obstetrics and Gynecology·Jeremy ChipchaseCharles Rodeck
Jul 17, 1999·Progress in Neurobiology·P L Madsen, N H Secher
Mar 29, 2000·Clinical Physiology·P L MadsenP Christiansen
May 26, 2012·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·S ViolaL Fiorelli
Sep 24, 2004·Archives of Gerontology and Geriatrics·Larisa P SafonovaEnrico Gratton
May 16, 2006·Respiratory Physiology & Neurobiology·Juha E PeltonenJ Kevin Shoemaker
Jun 5, 2015·Lasers in Surgery and Medicine·Christopher R IdelsonChristopher G Rylander
Oct 6, 2017·High Altitude Medicine & Biology·Francesca LanfranconiGiuseppe Andrea Miserocchi
May 4, 2010·Physics in Medicine and Biology·T E J NoponenP T Meriläinen
Apr 14, 2007·Journal of Applied Physiology·Andrew W SubudhiRobert C Roach
Jan 29, 2000·Anesthesia and Analgesia·A T LovellJ C Goldstone
May 28, 2005·Journal of Applied Physiology·C H E ImrayA D Wright
Feb 21, 2007·Journal of Applied Microbiology·C SantivarangknaU Kulozik
Apr 20, 2001·Journal of Cardiothoracic and Vascular Anesthesia·H L Edmonds

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