PMID: 1210984Jan 1, 1975Paper

The effect of several psychotropic substances on brain structure

Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova
E N Popova, G N Krivitskaia

Abstract

The authors have shown similarities of structural changes in the neuron and interneuronal relations found in the brains of rats under indopan and LSD stimulation of the CNS with certain differences in the localization of the changes in the functionally different brain systems. A high sensitivity of the sensory-motor cortex and the subcortical formations of the brain, rich in dopamine and serotonin, to indopan has been marked. LSD central effects were conditioned by the influence of the drug not only on the synapsis, but on the cell body components of the different brain systems, especially in the visual. The observed changes were allocated to categories of functional disturbances.

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