The Effect of Short-term Treatment with Fennel on Lipid Profile in Postmenopausal Women: A Randomized Controlled Trial

Journal of Menopausal Medicine
Maliheh AfiatHassan Rakhshandeh

Abstract

The present trial aimed to assess the effects of Fennel (Foeniculum vulgare Mill.) on lipid profiles. In this double blind, randomized and placebo-controlled trial, sixty eligible postmenopausal women were randomly assigned into the fennel and placebo groups. Total blood cholesterol, cholesterol fractions, and triglycerides were tested at the baseline, and after three-month follow-up. There was no significant difference in triglyceride (P = 0.679), total cholesterol (P = 0.103), low-density lipoprotein cholesterol (LDL-C; P = 0.146) and high-density lipoprotein cholesterol (HDL-C; P = 0.266) levels between the two groups. In addition, in both groups, a paired t.test showed no significant difference in all mentioned parameters, except for HDL-C, indicating significant borderline improvement (P = 0.052) in the fennel group. The fennel group revealed a very slight positive change in LDL-C, triglyceride and HDL-C. Further studies with longer durations, higher doses, and larger sample sizes are recommended to validate the results.

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Sep 28, 2017·Journal of Menopausal Medicine·Masumeh GhazanfarpourMaliheh Afiat

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Citations

Jul 3, 2019·Current Pharmaceutical Biotechnology·Georgia-Eirini DeligiannidouTheodoros Constantinides
Mar 17, 2021·Complementary Therapies in Clinical Practice·Hye Won LeeMyeong Soo Lee

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