The effect of sleep intervals on analysis of 24-h ambulatory blood pressure data

American Journal of Hypertension
S J RosanskyK Jackson

Abstract

Twenty-four hour blood pressure exposure and circadian blood pressure variability may be important predictors of hypertensive end-organ damage. Since sleep is a major determinant of circadian blood pressure decline, day/night blood pressure changes may be affected by sleep intervals. The current study compares 24-h blood pressure results with and without adjustment for patient-specific sleep intervals. Forty male hypertensive patients (22 with renal insufficiency and 18 with normal renal function) underwent 24-h blood pressure study with SpaceLabs 90207 monitors. They also filled out sleep questionnaires to evaluate time awake and asleep during the day and night intervals. Data was analyzed with and without adjustment for daytime asleep and nighttime awake intervals. The percent change in systolic, diastolic, and mean arterial pressure as well as heart rate was not different statistically or clinically with or without adjustment for sleep intervals. Nevertheless, there was a progressive increase in the day versus night percent change in these hemodynamic parameters with adjustment for sleep intervals. When we used arbitrary cut-offs to define "non-dipper", ie, less than 10% drop in a given hemodynamic parameter, and used patien...Continue Reading

Citations

Aug 15, 1996·Annals of the New York Academy of Sciences·T G PickeringA Stone
Aug 17, 2005·Hypertension·Rajiv Agarwal, Martin J Andersen
Aug 4, 2006·Current Hypertension Reports·Giuseppe Mancia, Gianfranco Parati
Apr 28, 2005·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Natasa Marcun Varda, Alojz Gregoric
Apr 6, 2007·Journal of the American Society of Nephrology : JASN·Hani M WadeiStephen C Textor
Oct 18, 2000·Blood Pressure Monitoring·J E DimsdaleM Ziegler
Jul 23, 2003·Journal of the American Society of Nephrology : JASN·Stephen C TextorMark Stegall
Nov 25, 1997·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·G A Mansoor, W B White

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