The effect of social isolation, gender and familiarity with the experimental procedure on tests of porcine nociceptive thresholds

Veterinary Anaesthesia and Analgesia
Pierpaolo Di GiminianiMette S Herskin

Abstract

To investigate the effects of habituation and isolation on mechanical nociceptive thresholds in pigs at the pelvic limbs and at the tail. Prospective randomized multifactorial study. Thirty-two healthy castrated male (experiment 1), and 12 castrated male and 12 female (experiment 2) Danish Landrace×Yorkshire pigs, weighing 63.5±0.8 kg and 55.4±0.6 kg (the mean±SD, experiment 1 and 2, respectively). Mechanical nociceptive thresholds were quantified with a von Frey anesthesiometer applied to two distinct anatomical regions (tail and pelvic limbs). Pigs receiving the mechanical challenge in the pelvic limbs were tested inside a cage, whereas pigs exposed to stimuli at the tail region were tested in an open arena. For both experiments, the effect of familiarity to the procedure was evaluated by comparing thresholds of nociception in habituated versus naïve pigs. The presence of a companion animal was also evaluated in pigs receiving stimuli at the pelvic limbs. Pigs tested inside the cage were affected by the habituation to the procedure as indicated by the increase in willingness and time spent by the animals in the test cage. This effect was reflected in the lower mechanical nociceptive thresholds (medians with 25-75 percentiles)...Continue Reading

References

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Oct 9, 2012·European Journal of Pain : EJP·P Di GiminianiM S Herskin
Dec 9, 2014·Animal : an International Journal of Animal Bioscience·M S HerskinH E Jensen

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Citations

Oct 16, 2015·Veterinary Anaesthesia and Analgesia·Elena NalonFrank A M Tuyttens
Dec 15, 2016·Frontiers in Veterinary Science·Sarah H IsonKenneth M D Rutherford
Jul 24, 2020·Animals : an Open Access Journal From MDPI·Sandra FrahmSusanne Waiblinger
Aug 11, 2017·Animals : an Open Access Journal From MDPI·Heidi S LehmannGabrielle C Musk

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