PMID: 8602340Dec 1, 1995Paper

The effect of sodium hypochlorite on potential pathogenic traits of Candida albicans and other Candida species

Oral Microbiology and Immunology
B C WebbK W Knox

Abstract

Strains of Candida albicans, Candida krusei, Candida kefyr, Candida tropicalis, Candida parapsilosis and Candida guilliermondii were grown in the presence or absence of concentrations of sodium hypochlorite below the minimal inhibitory concentration and tested for a range of characteristics that may be associated with pathogenicity. Sodium hypochlorite is used routinely in hospitals in Australia for disinfection procedures, and these experiments were designed to assess the efficacy of hypochlorite as a sterilizing agent for acrylic dentures. Candida showed varying abilities to adhere to surfaces that may be present in the oral cavity. Sodium hypochlorite reduced the adhesion of all C. albicans strains and most other Candida species to both polystyrene and buccal epithelial cells. A biofilm of Streptococcus gordonii reduced the adhesion of most C. albicans strains and most other Candida species to polystyrene. However, Candida species were able to coaggregate with S. gordonii in suspension, with one strain of C. albicans, GDH 2346, showing greater coaggregating ability than the other strains or species. Sodium hypochlorite increased coaggregation of all C. albicans strains and most other Candida species. Examination of cell wall...Continue Reading

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Citations

Sep 18, 1998·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·G J PanagodaL P Samaranayake
Jun 25, 2008·Antimicrobial Agents and Chemotherapy·Jeniel E NettDavid R Andes
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Mar 17, 2007·Journal of Prosthodontics : Official Journal of the American College of Prosthodontists·Sabrina PavanAndré Ulisses Dantas Batista
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Sep 10, 2015·Microbiology Spectrum·Jyotsna Chandra, Pranab K Mukherjee

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