The effect of steatosis on echogenicity of colorectal liver metastases on intraoperative ultrasonography

Archives of Surgery
Mark G van VledderMichael A Choti

Abstract

To investigate the association of relative tumor echogenicity and hepatic steatosis in patients undergoing resection of colorectal liver metastases (CRLM). Prospective study. The Johns Hopkins Hospital. A total of 126 patients undergoing liver surgery for CRLM from January 1, 1998, through December 31, 2008, in whom 191 lesions had complete intraoperative ultrasonography images for review and adequate linked pathological data available. The intraoperative ultrasonography images were reviewed and scored for echogenicity (hypoechoic, isoechoic, or hyperechoic). In addition, a histopathologic review of the nontumorous liver tissue was performed, and the extent of steatosis was scored and correlated with tumor echogenicity. Of the patients undergoing surgery, 49 (38.8%) were found to have mild to severe steatosis. Of the 191 total CRLM visualized by intraoperative ultrasonography, 91 (47.6%) were found to be hypoechoic, 65 (34.0%) were isoechoic, and 35 (18.3%) were hyperechoic. In patients with steatosis, lesions were significantly more likely to be hypoechoic when compared with patients without steatosis (odds ratio, 4.17; 95% confidence interval, 1.87-8.47; P = .001). Echogenicity was independent of the cause of steatosis or res...Continue Reading

Citations

Oct 16, 2012·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Andrea RuzzenenteAlfredo Guglielmi
Mar 10, 2016·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Amber L Simpson, T Peter Kingham
May 17, 2014·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Guido TorzilliMarco Montorsi
May 9, 2014·IEEE Transactions on Medical Imaging·Atul Ingle, Tomy Varghese
Jul 26, 2017·Journal of Surgical Oncology·Georgios Antonios MargonisMatthew J Weiss
Jan 20, 2012·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Alessandro FerreroLorenzo Capussotti
Jan 27, 2019·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Linda M PakT Peter Kingham
Mar 28, 2017·Surgical Endoscopy·Pascale TinguelyHenrik Nilsson
Mar 19, 2019·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·G DesolneuxS Evrard
May 10, 2021·Trends in Molecular Medicine·Nina OgrincIsabelle Fournier

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