PMID: 16638295Apr 28, 2006Paper

The effect of subglottic secretion drainage on prevention of ventilator-associated lower airway infection

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
Shu-hong LiuLi-juan Zhang

Abstract

To assess the influence of subglottic secretion drainage (SSD) on the morbidity of ventilator-associated pneumonia (VAP) in mechanically ventilated patients. All studied patients who received mechanical ventilation (MV) estimated for more than 48 hours were intubated with a special type endotracheal tube with a small-bore cannula in the wall for SSD. The patients were randomly divided into two groups receiving SSD (group A) and usual care (non-SSD, group B) respectively. Bacterial culture of samples from lower airway secretion taken regularly by Bagpipe Protected specimen brush were performed, and at the same time the subglottic secretion and scraping-pharynx specimen were collected for bacterial quantitative culture and antibiotic sensitivity test. The clinical data were recorded and the duration of MV, the length of stay in hospital and the time of occurrence of ventilator-associated airway infection (VAAI) and VAP were analyzed. (1) In patients with MV < 5 days: The incidence of VAAI and VAP in group A (VAAI: 8.3% and VAP: 6.0%) was lower than those in group B (VAAI: 24.0% and VAP: 20.0%, P < 0.05). The onset of VAAI and VAP was delayed in group A [VAAI: (7.4 +/- 3.0) d and VAP: (7.7 +/- 3.2) d] as compared with group B [VAA...Continue Reading

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