PMID: 7580754Jul 1, 1995Paper

The effect of tetrachloromethane and ethanol on the release by rat splenocytes of immunomodulating factors

Eksperimental'naia i klinicheskaia farmakologiia
M Iu SmakhtinG A Chalyĭ

Abstract

In combined introduction tetrachloromethane (TCM) and ethanol the spleen cells secrete both immunostimulating agent with a molecular mass (MM) of 10 - 25 kD and immunosuppressing agents with MM > 100 kD. Sticking and nonsticking to the glass splenocytes of the animal affected by TCM and ethanol, excrete, respectively, the immunostimulating or immunosuppressing agents to the supernatant liquid of the splenocytes.

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