The Effect of Time on Root Coverage Outcomes: A Network Meta-Analysis

Journal of Dental Research
Lorenzo TavelliHom-Lay Wang

Abstract

The stability of root coverage outcomes has gained a great deal of interest. However, insufficient evidence is available, mainly due to limited direct comparisons among different techniques and the small sample size among clinical trials. Therefore, the aim of this study was to propose a mixed-models network meta-analysis (NMA) that includes the novelty of assessing time on root coverage outcomes while simultaneously comparing different surgical approaches. A literature search was performed by 2 individual reviewers to identify randomized clinical trials (RCTs) reporting the outcomes of root coverage procedures of at least 2 time points to estimate the slopes of different treatment approaches. The primary outcomes were the changes in slopes for recession depth (REC), keratinized tissue width (KTW), and clinical attachment level. Sixty RCTs with a total of 2,554 gingival recessions (1,864 patients) were included in the NMA. Connective tissue graft (CTG) and enamel matrix derivative (EMD) approaches provided superior initial REC reduction compared to flap advancement alone. However, only CTG-based procedures were effective in maintaining the stability of the gingival margin over time, while EMD, acellular dermal matrix, collagen ...Continue Reading

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Citations

Aug 29, 2019·Journal of Periodontology·Giovanni ZucchelliWilliam V Giannobile
Sep 4, 2019·Journal of Periodontology·Lorenzo TavelliWilliam V Giannobile
Sep 3, 2019·Journal of Periodontology·Lorenzo TavelliWilliam V Giannobile
May 12, 2020·Journal of Periodontology·Shayan BarootchiHom-Lay Wang
Jul 13, 2020·Journal of Clinical Periodontology·Francesco CairoMaurizio Tonetti
Sep 26, 2020·International Dental Journal·Jean-Claude Imber, Adrian Kasaj
Oct 25, 2020·Journal of Periodontology·GiovanPaolo Pini Prato, Riccardo Di Gianfilippo
Nov 6, 2020·Journal of Periodontology·Giulio RasperiniWilliam V Giannobile
Nov 21, 2020·Clinical Advances in Periodontics·Gerardo José Chacón RamírezHom-Lay Wang
Feb 11, 2021·Clinical and Experimental Dental Research·Kristina BertlAndreas Stavropoulos
Apr 27, 2021·JDR Clinical and Translational Research·M AgustoG P Schincaglia
May 25, 2021·International Dental Journal·Jean-Claude Imber, Adrian Kasaj
Jul 9, 2021·Clinical Advances in Periodontics·Debora FranceschiRiccardo Di Gianfilippo
Dec 1, 2021·Clinical and Experimental Dental Research·Sourav PandaMassimo Del Fabbro

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