PMID: 37770Jul 2, 1979

The effect of timolol and parasympathicomimetica in the treatment of the elevated intraocular pressure (author's transl)

Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Albrecht Von Graefe's Archive for Clinical and Experimental Ophthalmology
M Ober, A Scharrer

Abstract

45 patients with ocular hypertension or open-angle glaucoma were tested to see if, and to what extent timolol and three other different parasympathicomimetics (pilocarpine 2%, carbachol 1.5%, aceclydine 2%) produced an supplementary reduction of the intraocular pressure. An equally marked, additional drop in eye pressure was achieved when patients who had been given timolol over an extended period of time, were additionally treated with one dose of pilocarpine 2% or carbachol 1.5%. Aceclydine 2% produced no statistically significant additional effect. Patients who had only been treated with pilocarpine 2% over an extended period of time and then were given one dose of timolol 0.25% produced a drop in eye presure more than double that of those patients who had been primarily treated with timolol and then received pilocarpine or carbachol. These results will be discussed on the basis of the mode of action of the applied medications.

Citations

Oct 1, 1978·Acta Ophthalmologica·E Kerty, I Hørven
Apr 1, 1977·Archives of Ophthalmology·T J Zimmerman, H E Kaufman
May 1, 1978·The British Journal of Ophthalmology·K WettrellM Pandolfi
Jan 1, 1979·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·M OberK Porkert
Aug 1, 1978·Experimental Eye Research·M E YablonskiB Becker
Jan 1, 1971·Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Albrecht Von Graefe's Archive for Clinical and Experimental Ophthalmology·H Meythaler, W Ruppert
Jan 1, 1968·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·G Niemeyer

Related Concepts

Ocular Hypertension
Carboptic
Quinuclidines
Propanolamines
Parasympathomimetic Effect
Salagen
Physiologic Intraocular Pressure
Glaucoma, Open-Angle
Drug Administration Schedule
Glaucoma

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