PMID: 7008894Mar 1, 1981Paper

The effect of topical povidone-iodine on the incidence of infection in surgical wounds

The British Journal of Surgery
J A WalshJ J Finlay-Jones

Abstract

A randomized stratified clinical trial of topical povidone-iodine in 627 patients undergoing abdominal procedures demonstrated a reduction in postoperative wound sepsis in female patients, in patients receiving subcutaneous low dose heparin and during the first quarter of the trial when the infection rate in control subjects was high. Overall, there was no significant reduction in wound sepsis after administration of povidone-iodine due mainly to a high infection rate in povidone-iodine treated male appendix operations where, by chance, there was an increased incidence of contamination with Bacteroides fragilis. Postoperative stay in those developing wound infection was significantly reduced in the povidone-iodine group. This is considered as indirect evidence for a decrease in severity of wound infection.

Citations

May 1, 1982·World Journal of Surgery·J M WattsP J Woods
Jul 5, 2002·World Journal of Surgery·Gerald T McGrealH Paul Redmond
Jul 19, 2012·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Anthony M Rossi, Kavita Mariwalla
Jun 1, 1982·Postgraduate Medical Journal·H Ellis
May 11, 2005·Journal de chirurgie·C MarietteUNKNOWN Société Française de Chirurgie Digestive
Jul 27, 2007·International Wound Journal·Rose A Cooper
Sep 30, 2010·The British Journal of Surgery·I FournelL S Aho Glélé
Dec 1, 1984·The Australian and New Zealand Journal of Surgery·M G O'RourkeM E Wilson
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May 3, 2008·Revista da Escola de Enfermagem da U S P·Alcicléa dos Santos Oliveira, Vera Lúcia Conceiçõ de Gouveia Santos

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