The effect of training on strength and endurance of the diaphragm in quadriplegia

The American Journal of Medicine
D GrossA Grassino

Abstract

The diaphragmatic electromyogram was used to detect fatigue of the diaphragm in six chronic quadriplegics while they breathed for 10 minutes against a variety of inspiratory resistances. The maximum static inspiratory mouth pressure was measured at functional residual capacity (Pmmax) and from the electromyogram the critical inspiratory mouth pressure that developed in each inspiration (Pmcrit) below which electromyographic changes of diaphragmatic fatigue do not develop was estimated. The measurements were repeated after 8, 12 and 16 weeks of inspiratory muscle training consisting of inspiring for a period of 30 minutes daily, six days a week, against a resistance just sufficient to produce the electromyographic changes of fatigue. A significant and progressive increase in Pmmax and Pmcrit was found during the training. It was concluded that (1) quadriplegics are predisposed to the development of inspiratory muscle fatigue due to reduced muscle strength and reduction in endurance, and (2) in these patients inspiratory muscle training increases both strength and endurance, and protects against fatigue.

References

Jun 1, 1978·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·T G KeensC D Ianuzzo
Jan 1, 1979·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·D GrossP T Macklem
May 1, 1979·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·C RoussosP T Macklem
Oct 1, 1977·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·L LindströmI Petersén
Aug 1, 1977·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·C S Roussos, P T Macklem
Oct 1, 1976·Journal of Applied Physiology·D E Leith, M Bradley
Feb 1, 1973·Journal of Applied Physiology·D A LiebermanL C Maxwell
Mar 1, 1972·The American Journal of Physiology·D A LiebermanJ A Faulkner
Oct 12, 1968·British Medical Journal·J R Silver, N O Gibbon
Jun 1, 1968·Respiration Physiology·S M Tenney, R E Reese
Nov 1, 1960·Journal of Applied Physiology·G P ZOCCHEA COURNAND

Citations

Jan 1, 1987·European Journal of Applied Physiology and Occupational Physiology·D VilozniS Godfrey
Oct 1, 1986·Italian Journal of Neurological Sciences·A Lissoni, F Molteni
Nov 1, 1987·Medical & Biological Engineering & Computing·C G KramerB Kemp
Jan 1, 1982·Lung·C Roussos
Jun 1, 1987·Paraplegia·R E Carter
Feb 1, 1991·Paraplegia·F Biering-SørensenI Christensen
Jun 1, 1992·Paraplegia·C SinderbyL Lindström
Sep 23, 1982·The New England Journal of Medicine·C Roussos, P T Macklem
May 3, 1984·The New England Journal of Medicine·W W GlennR Rowedder
Mar 20, 1986·The New England Journal of Medicine·A De TroyerA Heilporn
Oct 28, 2006·Journal of Rehabilitation Medicine·Gabi MuellerChristina M Spengler
Dec 7, 1985·British Medical Journal·B P GardnerK R Krishnan
Sep 1, 1981·Journal of Neurology, Neurosurgery, and Psychiatry·J R Silver, R P Lehr
Mar 28, 1998·American Journal of Respiratory and Critical Care Medicine·H RollierM Decramer
May 1, 1989·The American Review of Respiratory Disease·M EstenneA De Troyer
Aug 1, 1989·The American Review of Respiratory Disease·P WeinerR M Cherniack
Jun 27, 2003·American Journal of Respiratory and Critical Care Medicine·Franco Laghi, Martin J Tobin
Dec 21, 2012·Journal of Strength and Conditioning Research·Marlene A MorenoRicardo M L Barros
Nov 30, 2007·International Journal of Chronic Obstructive Pulmonary Disease·Luis Puente-Maestu, William W Stringer
Sep 1, 1993·Paraplegia·R A CooperS Monical
Dec 1, 1982·IEEE Transactions on Bio-medical Engineering·F B Stulen, C J De Luca
Jan 1, 1992·The Australian Journal of Physiotherapy·A J Piper
Feb 20, 2004·Computers in Biology and Medicine·C NarasimhanG Mahinthakumar
Dec 1, 1982·Chest·M J Belman, G C Sieck
Dec 1, 1984·Chest·L J Sonne
May 1, 1989·JPEN. Journal of Parenteral and Enteral Nutrition·H E DemeyL L Bossaert
Dec 25, 2003·Muscle & Nerve·Christophe PerrinNicholas S Hill
Jul 25, 2013·The Cochrane Database of Systematic Reviews·David J Berlowitz, Jeanette Tamplin
May 15, 2002·Clinical Physiology and Functional Imaging·Stéphane V BerdahYves Jammes
Dec 21, 2018·Expert Review of Neurotherapeutics·Danique L M RadderBastiaan R Bloem

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