PMID: 5911513Mar 1, 1966

The effect of ultraviolet irradiation on collagen-fold formation

The Biochemical Journal
D R Cooper, R J Davidson

Abstract

1. A study has been made of the effect of ultraviolet irradiation, in the presence of air and nitrogen, on the conformational changes taking place in cooled solutions of gelatin prepared from thermally denatured neutral-salt-soluble collagen. 2. The increase in negative rotation and viscosity at 15 degrees for irradiated and thermally denatured solutions of collagen becomes less as the irradiation time is increased. 3. The principal effect of ultraviolet irradiation is the fission of the primary collagen peptide chains, eventually yielding chain lengths incapable of stabilizing a helical structure. 4. Irradiation in both air and nitrogen results in a loss of tyrosine, histidine and phenylalanine, with more denaturation occurring in the presence of nitrogen.

Citations

Nov 1, 1995·Journal of Biomedical Materials Research·K S WeadockM G Dunn
May 10, 2008·Journal of Biomedical Materials Research. Part a·Dimitrios I ZeugolisGeoffrey Attenburrow
Oct 16, 2013·Antioxidants & Redox Signaling·Rachel E B WatsonMichael J Sherratt
Jan 1, 1975·International Journal of Peptide and Protein Research·F Friedberg, K N Nandedkar
Jul 8, 1967·Nature·R Consden, J A Kirrane
May 28, 2019·Journal of Materials Science. Materials in Medicine·Adilet BeishenalievHwei-San Loh
Jun 29, 1978·Archives of Dermatological Research·H Alpermann, H G Vogel
Dec 31, 2009·Journal of Dental Research·M HayashiS Ebisu
Mar 23, 2002·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Alexander J MajewskiPeter Torzilli
Apr 8, 2021·Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada·Chao-Wei HungGuan-Yu Zhuo

Related Concepts

Zyderm
Gelafusal
Protein Denaturation
Effects of Radiation
Solutions
Black Light, Ultraviolet
Viscosity
Physicochemical Phenomena

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