PMID: 32672695Jul 17, 2020Paper

THE EFFECT OF ULTRAVIOLET RADIATION ON THE ORGANIZATION AND STRUCTURE OF COLLAGEN FIBERS OF DERMIS

Georgian Medical News
S MyronchenkoN Ashukina

Abstract

The aim is to study the features of the influence of local ultraviolet radiation on the organization and structure of collagen fibers in the radiation area. The studies were performed on 30 albino guinea pigs weighing 400-500 g, exposed to local ultraviolet radiation. Animals were removed from the experiment after 2 hours, 4 hours, 3 days, 8 days after irradiation. The control group was intact guinea pigs. To assess the structure and location of collagen fibers, skin sections in the irradiated area were studied using histological methods with polarized light analysis of collagen, and they were also analyzed using a scoring system for three parameters: composition, refraction intensity, and orientation of collagen fibers. The revealed structural features of collagen fibers reflect the course of the process of degeneration of the collagen skeleton of the dermis with a violation of the orientation and ordering of collagen fibers and an increase in the content of type III collagen with an increase in the observation period. According to the results of a semi-quantitative assessment of the state of collagen fibers, a significant deterioration in their structure and composition was recorded starting from 4 hours after exposure to ult...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Asian Pacific Journal of Tropical Medicine
Qi-Tao WenCui-Wei Liang
Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
Y TianN Ketheesan
© 2021 Meta ULC. All rights reserved