PMID: 20654220Jul 27, 2010Paper

The effect of Vaccinium uliginosum to the electroretinogram and retina of rabbits before and after light-induced damage

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology
Lan YinMao-nian Zhang

Abstract

Study the effect of Vaccinium uliginosum (VU) on the electroretinogram (ERG) and histology of rabbits' retina before and after light-induced damage. It was an experimental study in contrast. Thirty-five Chinchilla Rabbits were divided into five groups according to the randomization tables. All rabbits ate and drank freely except those in group A and D who were fed with VU homogenate. Four weeks later we observed the tissue & structure of the rabbits in group D and E under the light microscope and measured the thickness of their out nuclear layers (ONL) and apoptosis index (AI). At the same time, we recorded maximal combined reaction ERG and oscillatory potentials (oscillatory potentials, OPs) of the left rabbits according to the standards set by the International Society for Clinical Electrophysiology of Vision (ISCEV). Then group A, B and C were exposed to strong light. Also we stopped feeding group A with VU and start to feed group C with it. We recorded ERG of them all after 1 day, 1 week and 2 weeks respectively. Then we observed the tissues & structures of them. SPSS 12.0 software package was used for one-way or double ways ANOVA and LSD test. (1) Maximal combined reaction ERG: after four weeks feeding implicit time of gro...Continue Reading

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