Abstract
CVD remains the major cause of death for dialysis patients. Dialysis patients have both traditional and nontraditional risk factors, including the retention of advanced glycation end products (AGE). Tissue AGE can be measured by skin autofluorescence (SAF) and are a reliable measurement of chronic exposure. Dietary intake of AGE may be lower in vegetarian patients than in non-vegetarian patients, so we determined whether vegetarian patients had lower SAF than non-vegetarian patients. We measured SAF in 332 adult haemodialysis patients using a UV technique in a standardised manner. Information about patients' demographic data, laboratory results and current medicinal prescriptions was collected retrospectively from the hospital's computerised database. The mean patient age was 65·2 (SD 15·1) years, 64 % were men, 42 % were diabetic, and 66 % were Caucasian. The mean SAF was 3·26 (SD 0·95) arbitrary units (AU), and SAF was lower in vegetarians as compared to non-vegetarians (2·71 (SD 0·6) v. 3·31 (SD 0·97) AU, P= 0·002). SAF was negatively correlated on both univariate (r -0·17, P= 0·002) and multiple linear regression (β coefficient -0·39, 95 % CI -0·7, -0·07, P= 0·019). SAF, a marker of tissue AGE deposition, was reduced in veg...Continue Reading
References
Jun 10, 1997·Proceedings of the National Academy of Sciences of the United States of America·T KoschinskyH Vlassara
Feb 22, 2003·Journal of the American Society of Nephrology : JASN·Jaime UribarriHelen Vlassara
Nov 11, 2005·Journal of the American Society of Nephrology : JASN·Robbert MeerwaldtAndries J Smit
May 14, 2008·Diabetes Technology & Therapeutics·Alin StirbanDiethelm Tschoepe
Jul 30, 2008·Nephron. Clinical Practice·Belinda MoreyAndrew Davenport
Aug 14, 2009·Nephrology·Andrew Davenport
Feb 20, 2010·Lancet·Andrew Davenport, Ken Farrington
May 26, 2010·Journal of the American Dietetic Association·Jaime UribarriHelen Vlassara
Jul 20, 2010·Optics Express·M KoetsierReindert Graaff
Nov 13, 2010·Nephron. Clinical Practice·Katherine VernonAndrew Davenport
Dec 7, 2011·Hemodialysis International·Andrew Davenport
Apr 12, 2012·Clinical Journal of the American Society of Nephrology : CJASN·Kajal P PatelTimothy W Meyer
Jan 18, 2013·Kidney International·Hans-Joachim AndersBärbel Stecher
Jan 25, 2013·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·James E TattersallUNKNOWN EUDIAL group
Oct 30, 2013·Artificial Organs·Reindert GraaffBernd Stegmayr
May 2, 2014·Seminars in Nephrology·Joachim JankowskiAlessandra F Perna
Citations
Nov 26, 2015·Nutrition·Sho-Ichi Yamagishi, Takanori Matsui
May 28, 2015·Nephrology·Arkom Nongnuch, Andrew Davenport
Apr 6, 2016·Hemodialysis International·Sakina KandouzAndrew Davenport
Jan 16, 2018·Nature Reviews. Nephrology·Peter StenvinkelRichard J Johnson
Apr 4, 2018·Artificial Organs·Arkom Nongnuch, Andrew Davenport
Sep 21, 2017·PloS One·Muhammad Saeed AhmadElaine Holmes
Oct 10, 2018·Nephrology·Surachet VongsanimAndrew Davenport
Jun 24, 2020·Artificial Organs·Theerasak TangwonglertAndrew Davenport
Oct 8, 2019·Current Opinion in Nephrology and Hypertension·Daniela Viramontes Hörner, Maarten W Taal
Jul 14, 2020·PLoS Medicine·Adam ShardlowMaarten W Taal
Jun 29, 2017·European Journal of Nutrition·Nicole J KellowChristopher M Reid
Jan 5, 2019·European Journal of Clinical Nutrition·Debora M SilvaMaria do Rosário G Peixoto
May 6, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Jonas WizentyTilo Wuensch
Nov 22, 2018·Biomedical Optics Express·Maiko HermsmeierKin F Chan
Oct 7, 2021·PloS One·Arkom NongnuchAndrew Davenport