The Effectiveness and Safety of Micropulse Cyclophotocoagulation in the Treatment of Ocular Hypertension and Glaucoma.

Ophthalmology. Glaucoma
Qayim KabaDarana Yuen

Abstract

To evaluate the effectiveness and safety of primary and adjunctive micropulse cyclophotocoagulation (MPCPC) in the treatment of ocular hypertension (OHT) and glaucoma. Retrospective cohort study. Ocular hypertension and all severities of glaucoma (including treatment-naïve and well-sighted eyes) and all types of glaucoma (including normal-tension glaucoma [NTG]). Consecutive eyes with glaucoma or OHT that underwent MPCPC (Iridex Cyclo G6 Glaucoma Laser System, Mountain View, CA) between 2016 and 2018 were identified. Intraocular pressure (IOP), visual acuity, glaucoma medications, and ocular adverse events. Three hundred ninety-nine MPCPC surgeries, on 342 eyes of 214 patients, were analyzed. Laser power ranged from 900 to 2800 mW. Main diagnoses in descending prevalence were primary open-angle glaucoma (55.9%), chronic angle-closure glaucoma (10.8%), neovascular glaucoma (9.0%), NTG (6.5%), and OHT (5.5%). Mean baseline IOP was 19.8±7.4 mmHg and IOP reduction was 22.7%, 20.2%, 20.7%, and 23.7% at postoperative months (POMs) 1, 3, 6, and 12 (P < 0.0001 for all time points). The end point of 20% or more mean IOP reduction from baseline was achieved by 67.8% of the study cohort at POM 12. Additional mean IOP reduction of 16.4% (P...Continue Reading

References

Feb 1, 1979·Archives of Ophthalmology·J B Wise, S L Witter
Jan 15, 1992·American Journal of Ophthalmology·H L Hennis, W C Stewart
Mar 1, 1989·The British Journal of Ophthalmology·R H GrayW H Ayliffe
Apr 1, 1973·American Journal of Ophthalmology·A R Bellows, W M Grant
Jan 1, 1970·Archives of Ophthalmology·D S Walton, W M Grant
Aug 1, 1961·American Journal of Ophthalmology·R WEEKERSA M LEGROS
Jul 1, 1955·American Journal of Ophthalmology·L L COVELL, R T BATUNGBACAL
Mar 5, 2010·Journal of Refractive Surgery·Antonio Rodríguez-GalieteroJosé Angel Cristóbal Bescós
May 8, 2010·Clinical & Experimental Ophthalmology·Anna M TanPaul Tk Chew
Feb 22, 2011·Journal of Glaucoma·Norlina RamliShamira Perera
Jan 17, 2012·American Journal of Ophthalmology·Steven J GeddeUNKNOWN Tube versus Trabeculectomy Study Group
Jul 4, 2013·Journal of Refractive Surgery·Theodore A PasqualiDaniel S Durrie
May 9, 2014·Clinical & Experimental Ophthalmology·Maria Cecilia D AquinoPaul Tk Chew
Dec 31, 2015·Lasers in Medical Science·Sarah KucharMichael Waisbourd
Jul 4, 2017·Journal of Glaucoma·Matthew E EmanuelSwati Goyal
Jul 25, 2017·The Ocular Surface·Jennifer P CraigFiona Stapleton
Oct 17, 2017·The Lancet Global Health·Seth R FlaxmanUNKNOWN Vision Loss Expert Group of the Global Burden of Disease Study
Feb 7, 2018·Journal of Ophthalmic & Vision Research·Jideofor K NdulueMarlene R Moster
Nov 19, 2018·Advances in Therapy·Anna I DastiridouAnastasios-Georgios Konstas
Mar 11, 2019·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Paul Rafuse, Yvonne M Buys
Jan 1, 2019·Ophthalmology. Glaucoma·Soshian SarrafpourNathan M Radcliffe

❮ Previous
Next ❯

Citations

Nov 12, 2020·Ophthalmology. Glaucoma·Darana YuenSohel Somani
Mar 6, 2021·Archivos de la Sociedad Española de Oftalmología·Amr Mohamed ELGwailyAhmed A Meguid A Latif Latif
Jul 17, 2020·Ophthalmology. Glaucoma·Harry A Quigley
Oct 26, 2021·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Sanchay GuptaDavid A Solá-Del Valle

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.