The Effectiveness of a Risk Stratification Protocol for Thromboembolism Prophylaxis After Hip and Knee Arthroplasty

The Journal of Arthroplasty
Denis NamRobert L Barrack

Abstract

This study's purpose was to present our institution's experience with the use of a risk stratification protocol for venous thromboembolism (VTE) prophylaxis in joint arthroplasty in which "routine" risk patients receive a mobile compression device in conjunction with aspirin and "high"-risk patients receive warfarin for thromboprophylaxis. This was a prospective study of patients undergoing primary or revision knee or hip arthroplasty. Exclusion criteria were patients with a current deep vein thrombosis, history of pulmonary embolism, chronic warfarin therapy, planned multiple surgeries, and prolonged postoperative immobilization. Patients were stratified as either routine or high risk. Routine risk patients received mobile compression devices for 10 days and aspirin twice daily for 6 weeks, whereas high-risk patients received warfarin for 4 weeks and compression stockings for 6 weeks. A total of 3143 total joint arthroplasties were enrolled (2222, 70.7% "routine"; 921, 29.3% "high risk"). The rate of symptomatic VTE within 6 weeks postoperatively was 0.7% (95% CI 0.3%-1.0%) in the standard vs 0.5% (95% CI 0.01%-1.0%) in the high-risk cohort (P = .67), and within 6 months postoperatively was 0.6% (95% CI 0.3%-1.0%) in the stand...Continue Reading

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Citations

Sep 23, 2016·The Journal of Bone and Joint Surgery. American Volume·James T NinomiyaStephen J Incavo
Jul 22, 2016·Foot & Ankle International·James R McWilliam, Gordon Mackay
Mar 13, 2018·Clinical Orthopaedics and Related Research·Diren ArsoySteven T Woolson
Apr 18, 2019·The Journal of Bone and Joint Surgery. American Volume·Michael J DeRogatisPaul S Issack
Feb 7, 2020·F1000Research·Rocco Aicale, Nicola Maffulli
Jan 4, 2017·The Bone & Joint Journal·J HaynesD Nam
Sep 20, 2017·The Journal of Bone and Joint Surgery. American Volume·James T NinomiyaStephen J Incavo
Feb 20, 2021·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Zakk M BortonPeter W Howard

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